Skip to main content
Clinical Trials/NCT01571492
NCT01571492
Completed
Not Applicable

Continuous L2 Paravertebral Block Versus Continuous Lumbar Plexus Block for Postoperative Analgesia After Total Hip Arthroplasty

University of Pittsburgh1 site in 1 country60 target enrollmentJune 2009

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Total Hip Arthroplasty
Sponsor
University of Pittsburgh
Enrollment
60
Locations
1
Primary Endpoint
Postoperative Opiate consumption
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

This prospective study is intended to compare the analgesic efficacy, preservation of lower extremity motor power and side-effect profile of L2 Paravertebral lumbar plexus approach compared to Posterior nerve stimulation guided lumbar plexus approach, continuous local anesthetic infusion postoperative analgesia of Total Hip Arthroplasty.

The L2 Paravertebral technique of lumbar plexus block, as part of a multimodal pain treatment, could be a cost-effective alternative with a equal profile of analgesic efficacy and motor power sparing with greater promotion of early achievement of postoperative physical therapy goals.

Detailed Description

The nerve stimulator guided technique of continuous lumbar plexus block (LPB) is the accepted standard of care at University of Pittsburgh Medical Center (UPMC) for the management of postoperative analgesia after Total Hip Arthroplasty. Over 900 continuous lumbar plexus blocks were performed at UPMC Presbyterian Shadyside hospital within the last year alone. Continuous thoracic paravertebral block (TPVB) is also commonly performed at UPMC Presbyterian Shadyside . Over 2000 are performed annually for a wide variety of surgical procedures. Recently authors have suggested that a lumbar paravertebral block (LPVB) may represent an alternative approach to the lumbar plexus. Indeed the L2 paravertebral approach of the lumbar plexus has been described to provide adequate postoperative analgesia following hip arthroscopic surgery. However, to date, there is no prospective direct comparison between L2 Lumbar plexus approach and the posterior approach for postoperative analgesia after Total Hip Arthroplasty.

Registry
clinicaltrials.gov
Start Date
June 2009
End Date
June 2015
Last Updated
8 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Jacques E. Chelly

Professor

University of Pittsburgh

Eligibility Criteria

Inclusion Criteria

  • Age between 18-75 years
  • No contraindications to placement of a lumbar plexus posterior block or paravertebral block.
  • ASA status I-III
  • Scheduled for open total hip arthroplasty with the same surgeon.
  • Patients without painful conditions or chronic use of opioid or antineuropathic medications.
  • Patient who are not expected to receive therapeutic anticoagulation in the postoperative period.
  • No Known allergies to the medications used in the study.
  • Patients willing to receive spinal anesthesia

Exclusion Criteria

  • Age under 18 years or older than 75 years.
  • Any contraindication to a placement of continuous lumbar plexus Block.
  • American Society of Anesthesiologist physical status IV or greater.
  • Chronic painful conditions.
  • Preoperative opioid tolerant use.
  • Coagulation Abnormalities or patients who are expected to be on therapeutic anticoagulants postoperatively.
  • Allergy to any of the drugs/agents used study protocol.
  • Personal or family history of malignant hyperthermia.
  • Serum creatinine greater than 1.4 mg/dl.
  • Pregnancy

Outcomes

Primary Outcomes

Postoperative Opiate consumption

Time Frame: 24 postoperatively

Postoperative Opiate consumption will be recorded as Morphine IV mg equivalent, for the first 24 hours.

Secondary Outcomes

  • NRS Pain Score (at rest)(24 and 48 hours postoperatively)
  • Long arc quad (LAQ)(24 hours postoperatively)
  • NRS Pain Score during physical therapy(24 and 48 hours postoperatively)
  • Straight Leg Raise(SLR)(24 hours postoperatively)
  • TUG (Timed Up and Go)(24 hours postoperatively)

Study Sites (1)

Loading locations...

Similar Trials

Active, not recruiting
Not Applicable
Comparison of continuous paravertebral blockade (PVB) and continuous thoracic epidural analgesia (TEA) for analgesia following open renal surgery
EUCTR2008-004998-17-IEDepartment of Anaesethesia
Completed
Not Applicable
Bilateral Paravertebral Blockade (T7-10) vs. Incisional Local Anesthetic Administration for Pediatric PatientsPain, Postoperative
NCT01380834Mihaela Visoiu84
Completed
Not Applicable
Efficacy of continuous paravertebral blocks in breast surgery
JPRN-UMIN000011610Gifu University Hospital Department of Anesthesiology&Pain Medicine60
Active, not recruiting
Not Applicable
A comparison of pain relief options after a mastectomy. A paravertebral block in an injection paralell to the spine and blocks the nerves suppling the surgical area. A wound catheter is place in the surgical wound and used to numb the area.This study will involve the administration of levobupivicaine 0.125% and 0.25%, a local anaesthetic agent licensed for this purpose into the paravertebral space and into the surgical wound, to provide postoperative analgesia for adults having a mastecomy. We aim to compare the analgesia efficacy of paravertebral blockade with surgical wound blockade for post operative pain in the first 48 hours.MedDRA version: 14.0Level: LLTClassification code 10054711Term: Postoperative painSystem Organ Class: 10022117 - Injury, poisoning and procedural complicationsTherapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]
EUCTR2011-002867-40-IEDepartment of Anaesthesia
Completed
Not Applicable
Erector Spinae Plane Block Versus Paravertebral Block for Analgesia After Cardiac Surgery (PEPS)Pain SyndromeAnalgesiaAnesthesia, Local
NCT04546113Institut Mutualiste Montsouris96