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Continuous L2 Paravertebral Block Versus Continuous Lumbar Plexus Block for Postoperative Analgesia

Not Applicable
Completed
Conditions
Total Hip Arthroplasty
Interventions
Procedure: L2 Paravertebral catheter nerve block
Procedure: Continuous Lumbar plexus nerve block
Registration Number
NCT01571492
Lead Sponsor
University of Pittsburgh
Brief Summary

This prospective study is intended to compare the analgesic efficacy, preservation of lower extremity motor power and side-effect profile of L2 Paravertebral lumbar plexus approach compared to Posterior nerve stimulation guided lumbar plexus approach, continuous local anesthetic infusion postoperative analgesia of Total Hip Arthroplasty.

The L2 Paravertebral technique of lumbar plexus block, as part of a multimodal pain treatment, could be a cost-effective alternative with a equal profile of analgesic efficacy and motor power sparing with greater promotion of early achievement of postoperative physical therapy goals.

Detailed Description

The nerve stimulator guided technique of continuous lumbar plexus block (LPB) is the accepted standard of care at University of Pittsburgh Medical Center (UPMC) for the management of postoperative analgesia after Total Hip Arthroplasty. Over 900 continuous lumbar plexus blocks were performed at UPMC Presbyterian Shadyside hospital within the last year alone. Continuous thoracic paravertebral block (TPVB) is also commonly performed at UPMC Presbyterian Shadyside . Over 2000 are performed annually for a wide variety of surgical procedures. Recently authors have suggested that a lumbar paravertebral block (LPVB) may represent an alternative approach to the lumbar plexus. Indeed the L2 paravertebral approach of the lumbar plexus has been described to provide adequate postoperative analgesia following hip arthroscopic surgery. However, to date, there is no prospective direct comparison between L2 Lumbar plexus approach and the posterior approach for postoperative analgesia after Total Hip Arthroplasty.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
60
Inclusion Criteria
  • Age between 18-75 years
  • No contraindications to placement of a lumbar plexus posterior block or paravertebral block.
  • ASA status I-III
  • Scheduled for open total hip arthroplasty with the same surgeon.
  • Patients without painful conditions or chronic use of opioid or antineuropathic medications.
  • Patient who are not expected to receive therapeutic anticoagulation in the postoperative period.
  • No Known allergies to the medications used in the study.
  • Patients willing to receive spinal anesthesia
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Exclusion Criteria
  • Age under 18 years or older than 75 years.
  • Any contraindication to a placement of continuous lumbar plexus Block.
  • American Society of Anesthesiologist physical status IV or greater.
  • Chronic painful conditions.
  • Preoperative opioid tolerant use.
  • Coagulation Abnormalities or patients who are expected to be on therapeutic anticoagulants postoperatively.
  • Allergy to any of the drugs/agents used study protocol.
  • Personal or family history of malignant hyperthermia.
  • Serum creatinine greater than 1.4 mg/dl.
  • Pregnancy
  • Having an altered mental status (not oriented to place, person, or time)
  • Any comorbid condition that, in the judgment of the consulting orthopedic surgeon, or intraoperative anesthesiologist, would proscribe the patient from any aspect of the study.
  • Patient refusal.
  • Lumbar plexus block performed with loss of resistance technique
  • Patient requiring postoperative management in the ICU
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Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
L2 Paravertebral peripheral nerve blockL2 Paravertebral catheter nerve blockL2 paravertebral peripheral nerve block catheter will be placed.
Continuous Lumbar plexus peripheral nerve blockContinuous Lumbar plexus nerve blockContinuous unilateral lumbar plexus peripheral nerve block catheter will be placed.
Primary Outcome Measures
NameTimeMethod
Postoperative Opiate consumption24 postoperatively

Postoperative Opiate consumption will be recorded as Morphine IV mg equivalent, for the first 24 hours.

Secondary Outcome Measures
NameTimeMethod
NRS Pain Score (at rest)24 and 48 hours postoperatively

Pain scores at Rest will be recorded at 24 and 48 Hours

Long arc quad (LAQ)24 hours postoperatively

In sitting position at the edge of the bed or chair. Patient is asked to extend lower leg fully on side that is being tested. If able, this is indicative that quad function is intact. If unable to fully extend knee, would indicate quad weakness.

NRS Pain Score during physical therapy24 and 48 hours postoperatively

Pain scores at Rest and During physical therapy will be recorded at 24 and 48 Hours

Straight Leg Raise(SLR)24 hours postoperatively

In supine position with the extremity being tested and contralateral flexed LE with foot flat on surface. Patient is instructed to lift extremity to level of contralateral knee. Inability to lift entire LE off of the surface to the level of the contralateral knee would be indicative of hip flexor weakness. If the patient is able to lift LE off of the surface, however the knee flexes/unable to maintain full knee extension, this is indicative of quad weakness.

TUG (Timed Up and Go)24 hours postoperatively

The timed get up and go test is a measurement of mobility. It includes a number of tasks such as standing from a seating position, walking, turning, stopping, and sitting down which are all important tasks needed for a person to be independently mobile.

Trial Locations

Locations (1)

UPMC Presbyterian Shadyside

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Pittsburgh, Pennsylvania, United States

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