Can skin grafting success rates in burn patients be improved by using a low friction environment?

Completed

• Conditions: Topic: Children, Injuries and emergencies; Subtopic: All Diagnoses, Injuries and Emergencies (all Subtopics); Disease: Injuries and Emergencies, All Diseases; Skin and Connective Tissue Diseases; Burns

• Registration Number: ISRCTN82599687
• Lead Sponsor: niversity Hospitals Bristol NHS Foundation Trust

Brief Summary

2018 results in https://bmjopen.bmj.com/content/8/6/e021886

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-11-19
• Study Completion: 2017-06-30
• Last Update Posted: 14 January 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

1. Aged between 4 weeks to 100 years
2. Study participant requiring skin grafting of burn injured skin as part of the planned care
3. Nursed on a bed and admitted overnight or longer to one of the three burns services

Exclusion Criteria

1. Patients who are ventilated or on inotropes
2. Patients in whom VAC dressings were used to maintain grafts
3. Patients in whom consent is not possible will be excluded from questionnaire & interviews. In the case of children, parents will consent to participation, with older children giving assent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Feasibility of using low-friction bedding in skin grafted, burn injured patients will be determined through interviews with patients and carers at 3 months.

Secondary Outcome Measures

Name	Time	Method
<br> Clinical outcomes<br> 1. Percentage graft loss as determined by consultant surgical team when graft failure has been confirmed<br> 2. Hospital re-admission rate<br> 3. Diagnosis of wound infection defined as positive swab results and prescription of antibiotics<br> 4. Validation of the iBID grafting and re-grafting rates for use as an outcome in a full trial<br><br> Patient reported measures:<br> 1. Pain scores assessed using age-appropriate standardised self-report questionnaire measures including Wong-Baker, FLACC, Modified Objective Pain Score, and Visual Analogue Scale/ Numeric Rating Scale at 12 and 24 hours post-graft for both the donor and graft sites<br> 2. Quality of life assessed using age appropriate EQ-5D questionnaires pre-operatively and within 28 days after injury<br>