Clinical Profile of Gullian Barre Syndrome in a rural hospital in Central India
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 45
- 试验地点
- 1
- 主要终点
- Prognosis of the disease will be studied based on the power improvement in all limbs.
研究概览
简要总结
In this thesis, focusing on the clinical profile of Guillain-Barré Syndrome (GBS), Prevalance of GBS and clinical outcomes can be known in a Rural Hospital in Central India.
Response to Treatment: Evaluating improvement or deterioration following treatments such as intravenous immunoglobulin (IVIG) or plasmapheresis.
Time to Peak Disability: Measures the time from symptom onset to the worst point of disability.
Time to Recovery: Assesses the duration from peak disability to significant recovery milestones, such as when patient will be able to walk independently can be known.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Confirmed Diagnosis: Patients with a confirmed diagnosis of GBS based on clinical criteria, electrophysiological studies, and cerebrospinal fluid analysis.
- •Age Range: Include patients of age above 18 years
- •Patients presenting with Acute flaccid Paralysis with 28 days of illness.
- •Consent: Patients or their guardians must provide informed consent to participate in the study.
排除标准
- •Patients with features of Hypokalemic periodic paralysis.
- •Patients with features of upper motor neuron signs and symptoms.
- •Patients admitted with history of exposure to toxins.
- •Patients with severe terminal illness.
- •Patients in whom the weakness progressed for more than 4 weeks.
- •Patients age less than 18 years of age 7.Patients with a chronic form of GBS, such as chronic inflammatory demyelinating polyneuropathy (CIDP), to maintain focus on the acute presentation.
结局指标
主要结局
Prognosis of the disease will be studied based on the power improvement in all limbs.
时间窗: at every 2 weeks for 6 months power will be assessed.
次要结局
- ICU requirement of the patient will be assessed for how many days.(at 2 weeks, 4 weeks, 6 weeks. for every 2 weeks assesemenet will be done)
研究者
Dr Mathaklala Aparna
Jawaharlal Nehru medical college