Natural Supplements for Unipolar Depression
Phase 4
Completed
- Conditions
- Unipolar Depression
- Interventions
- Drug: Supplements of L-methionine, betaine and folate
- Registration Number
- NCT00226356
- Lead Sponsor
- Cambridge Health Alliance
- Brief Summary
This study is being conducted to determine the clinical response rate for the regimen of L-methionine, betaine and folate for unipolar depression.
- Detailed Description
The study is 6 weeks long, with 9 clinical visits. All visits will take place at our location in Massachusetts.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
- DSM-IV diagnosis of a MDD or DDNOS; clinical indication for treatment of current depressive symptoms; HDS > 18; women of reproductive potential must use an acceptable method of birth control
Exclusion Criteria
- Treatment with another psychotropic drug; history of mania or hypomania; history of bipolar illness in first-degree relatives; active homicidality; pregnant; trying to become pregnant, or nursing; unstable medical condition; current substance abuse in the past month; history of sulfa allergy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Supplements of L-methionine, betaine and folate Supplements of L-methionine, betaine and folate -
- Primary Outcome Measures
Name Time Method Depressive symptoms
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Cambridge Health Alliance
🇺🇸Cambridge, Massachusetts, United States