Clinic Features and Long-term Outcome of Different Subgroups of Brochopulmonary Dysplasia in Preterm Infants
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Bronchopulmonary Dysplasia
- Sponsor
- Wang Jianhui
- Enrollment
- 300
- Locations
- 1
- Primary Endpoint
- Mortality
- Last Updated
- 4 years ago
Overview
Brief Summary
This study described the perinatal high-risk factors and clinical manifestations of the children, and compared the high-risk factors, clinical manifestations and prognosis of BPD among different clinical subtypes by comparison between groups. BPD grading was performed using the 2018 grading standard to compare the distribution of I/II/III BPD among different groups.
Investigators
Wang Jianhui
Attending doctor
Children's Hospital of Chongqing Medical University
Eligibility Criteria
Inclusion Criteria
- •Premature infants born at \<32 weeks of gestational age;
- •hospitalization time ≥ 14 days;
- •The clinical medical records are complete
Exclusion Criteria
- •• 1) Children with congenital heart, lung malformation and definite chromosomal diseases; 2) children gave up treatment halfway; 3) corrected gestational age 36 weeks before death, the cause of death was confirmed as factors other than respiratory system.
Outcomes
Primary Outcomes
Mortality
Time Frame: up to 12 months after birth
Different subtype of BPD infants against the total BPD infants in corresponding group
Duration of first hospital stay
Time Frame: up to 12 months after birth
days between admission and first discharge
Days with oxygen supplement
Time Frame: up to 12 months after birth
days during which the infants were given oxygen
Days of Mechanical Ventilation
Time Frame: up to 12 months after birth
days during which the infants were given mechanical ventilation
Serious respiratory mobidities
Time Frame: up to 18 months after birth
occurence of at least one of the following: tracheostomy, continued hospitalization for respiratory reasons at or beyond 50weeks PMA; continued oxygen supplement or respiratory support beyond 12months after birth; readmission for respiratory reasons.
Secondary Outcomes
- head circumference(up to 18months after birth)
- weight(up to 18months after birth)
- length(up to 18months after birth)