NL-OMON38745
Completed
Not Applicable
DETection of Early Radiation-induced Myocardial Injury using cardiac sympathetic inNErvation scintigraphy (DETERMINE) - Detection of radiation-induced myocardial injury after breast irradiation.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Medisch Centrum Haaglanden
- Enrollment
- 41
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\-Histological confirmed adenocarcinoma of the left or right breast
- •\-Operable breast carcinoma (clinically T1\-2; N0\-1\)
- •\-Breast conserving surgery (BCS) (and adequate axillary staging)
- •\-WHO performance: status \* 2
- •\- Patients participated in the calcium study \[NL18534\.098\.07 / 07\-090]
- •\- Written informed consent
Exclusion Criteria
- •\-Histology other than adenocarcinoma
- •\-Distant metastases (including non\-ipsilateral lymph node metastases)
- •\-Locally advanced (inoperable) breast cancer (clinically T3\-4; N2\-3\)
- •\-En bloc axillary dissection
- •\-Previous (non surgical) treatment of the breast carcinoma including pre\-operative chemotherapy or hormonal therapy
- •\-Neurodegenerative diseases (Multiple systemic atrophy, central autonomic failure)
- •\- Parkinson's disease.
- •\-Male gender
- •\-Pregnancy
- •Exclusion criteria for the MIBG scan:
Outcomes
Primary Outcomes
Not specified
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