NL-OMON38745已完成不适用
DETection of Early Radiation-induced Myocardial Injury using cardiac sympathetic inNErvation scintigraphy (DETERMINE) - Detection of radiation-induced myocardial injury after breast irradiation.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 41
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •-Histological confirmed adenocarcinoma of the left or right breast
- •-Operable breast carcinoma (clinically T1-2; N0-1)
- •-Breast conserving surgery (BCS) (and adequate axillary staging)
- •-WHO performance: status * 2
- •- Patients participated in the calcium study [NL18534.098.07 / 07-090]
- •- Written informed consent
排除标准
- •-Histology other than adenocarcinoma
- •-Distant metastases (including non-ipsilateral lymph node metastases)
- •-Locally advanced (inoperable) breast cancer (clinically T3-4; N2-3)
- •-En bloc axillary dissection
- •-Previous (non surgical) treatment of the breast carcinoma including pre-operative chemotherapy or hormonal therapy
- •-Neurodegenerative diseases (Multiple systemic atrophy, central autonomic failure)
- •- Parkinson's disease.
- •-Male gender
- •-Pregnancy
- •Exclusion criteria for the MIBG scan:
- •- Allergic to previous use of 123I-MIBG.
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