Balance and Falls in Multiple Sclerosis
- Conditions
- Multiple Sclerosis
- Interventions
- Other: Group balance training
- Registration Number
- NCT02209467
- Lead Sponsor
- Örebro County Council
- Brief Summary
The study hypothesis is that for people with moderate to severe multiple sclerosis postural balance and walking improve and the risk of accidental falls are reduced after participating in a specific training intervention of 7 weeks. The hypothesis is also the the effect remain a further 7 weeks post training.
Multiple Sclerosis (MS) is disease affecting the central nervous system. Walking and postural balance are often affected early in the course of the disease. The risk of falls is large. Many persons with MS have decreased trunk stability compared to healthy persons . In an earlier study including people with mild to moderate MS we found that a period of core stability exercises reduced the risk of falls. In this study the training concept will be applied for persons with more severe walking limitations.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 52
- diagnosed multiple sclerosis
- Expanded Disability Scale Score of 5-6.5
- walking speed of less than 0.8 m/s as tested on a 10 meter walking test
- Ongoing relapse
- Cognitive or language difficulties that prohibit participating in the intervention or performing the outcome measures
- Change in specific MS medication during the last 30 days
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Group balance training early start Group balance training Group balance training focusing on core stability exercises 2 times per week for 7 weeks and 2 home training sessions per weeks.
- Primary Outcome Measures
Name Time Method Change from baseline in Berg Balance Scale at 8 weeks baseline, 8 weeks
- Secondary Outcome Measures
Name Time Method Change from baseline in 10 repetitions Sit to stand test at 15 weeks baseline, 15 weeks Change from baseline in Trunk Impairment scale at 8 weeks baseline, 8 weeks Change from baseline in the Trunk Impairment Scale at 15 weeks baseline, 15 weeks Change from baseline in the 10 repetition Si to stand test at 8 weeks baseline, 8 weeks Change from baseline in the Berg Balance scale at 15 weeks baseline, 15 weeks Change from baseline on the Timed Up and Go test at 8 weeks baseline, 8 weeks Change from baseline on the Timed Up and Go test at 15 weeks baseline, 15 weeks Change from baseline on the10 meter walking test at 8 weeks baseline, 8 weeks Change from baseline on the 10 meter walking test at 15 weks baseline, 15 weeks Change from baseline on the 2 minutes walking test at 8 weeks baseline, 8 weeks Change from baseline on the 2 minutes walking test at 15 weeks baseline, 15 weeks Change from baseline in postural sway at 8 weeks baseline, 8 weeks Change from baseline in postural sway at 15 weeks baseline, 15 weeks postural sway in standing on the floor is assessed
Change from baseline on the Falls-Efficacy scale at 8 weeks baseline, 8 weeks Change from baseline on the Falls Efficacy scale at 15 weeks baseline, 15 weeks Change from baseline on the Fatigue Scale for Motor and Cognitive functions at 8 weeks baseline, 8 weeks Change from baseline on the Fatigue Scale for Motor and Cognitive functions at 15 weeks baseline, 15 weeks Change from baseline on the MS Walking Scale-12 at 8 weeks baseline, 8 weeks Change from baseline on the MS Walking scale-12 at 15 weeks baseline, 15 weeks The number of falls and accidental falls from baseline to 15 weeks the number of falls and accidental falls are noted by the participant in a study-specific falls diary.
Trial Locations
- Locations (7)
Physiotherapy department Gävle hospital
🇸🇪Gävle, Sweden
Rehab unit Karlskoga hospital
🇸🇪Karlskoga, Sweden
Primary Health Care
🇸🇪Linköping, Sweden
Neurorehab Mälarsjukhuset
🇸🇪Eskilstuna, Sweden
Nyköping hospital
🇸🇪Nyköping, Sweden
Rehab unit Västerås hospital
🇸🇪Västerås, Sweden
Physiotherapy department University hospital
🇸🇪Örebro, Sweden