Study of Talabostat + Docetaxel Versus Docetaxel in Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) After Failure of Platinum-Based Chemotherapy
- Conditions
- Carcinoma, Non-Small Cell Lung
- Registration Number
- NCT00243204
- Lead Sponsor
- Point Therapeutics
- Brief Summary
This Phase 3 study will compare the efficacy of talabostat plus docetaxel to docetaxel plus placebo in patients with Stage IIIB/IV NSCLC who have failed a platinum-based chemotherapy regimen.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 400
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (90)
Medical Specialists of Fairfield
🇺🇸Fairfield, Connecticut, United States
Maryland Oncology Hematology, PA
🇺🇸Columbia, Maryland, United States
Billings Clinic
🇺🇸Billings, Montana, United States
The Center for Cancer and Hematologic Disease
🇺🇸Cherry Hill, New Jersey, United States
Kansas City Cancer Centers, Southwest
🇺🇸Overland Park, Kansas, United States
William Beaumont Hospital
🇺🇸Troy, Michigan, United States
Oncology Care Associates, PLLC
🇺🇸St. Joseph, Michigan, United States
El Paso Cancer Treatment Center
🇺🇸El Paso, Texas, United States
Texas Oncology, PA
🇺🇸Ft. Worth, Texas, United States
Texas Cancer Center of Mesquite
🇺🇸Mesquite, Texas, United States
Allison Cancer Center
🇺🇸Midland, Texas, United States
Marshall Schreeder, MD
🇺🇸Huntsville, Alabama, United States
Medical Oncology, LLC
🇺🇸Baton Rouge, Louisiana, United States
Kentucky Cancer Clinic
🇺🇸Hazard, Kentucky, United States
Lucio Gordan, MD
🇺🇸Gainesville, Florida, United States
Swarna S. Chanduri, MD
🇺🇸Pomona, California, United States
Pasco Hernando Oncology Associates PA
🇺🇸Brooksville, Florida, United States
Veena Charu, MD
🇺🇸Anaheim, California, United States
Lalita Pandit, MD, Inc
🇺🇸Fountain Valley, California, United States
Citrus Hematology and Oncology Center
🇺🇸Inverness, Florida, United States
Nature Coast Clinical Research, LLC
🇺🇸Inverness, Florida, United States
Chesapeake Oncology Hematology Associates (Tate Center)
🇺🇸Glen Burnie, Maryland, United States
Jorge G. Otoya, MD
🇺🇸Kissimmee, Florida, United States
St. Joseph Oncology, Inc.
🇺🇸St. Joseph, Missouri, United States
Comprehensive Cancer Centers of Nevada
🇺🇸Las Vegas, Nevada, United States
Northern Indiana Oncology Associates
🇺🇸South Bend, Indiana, United States
Ocala Oncology Center
🇺🇸Ocala, Florida, United States
Hematology Oncology Associates of Illinois
🇺🇸Chicago, Illinois, United States
University of Chicago
🇺🇸Chicago, Illinois, United States
Indiana Hematology Oncology Consultants
🇺🇸Indianapolis, Indiana, United States
Pasco Hernando Oncology Associates, PA
🇺🇸New Port Richey, Florida, United States
Henry Ford Medical Center
🇺🇸West Bloomfield, Michigan, United States
Palmetto Hematology Oncology, PC
🇺🇸Spartanburg, South Carolina, United States
Texas Oncology Cancer Center
🇺🇸Austin, Texas, United States
Texas Cancer Center
🇺🇸Arlington, Texas, United States
Annandale-Fairfax Virginia Hematology Oncology, PC
🇺🇸Fairfax, Virginia, United States
Puget Sound Cancer Centers
🇺🇸Seattle, Washington, United States
Virginia Oncology Associates
🇺🇸Norfolk, Virginia, United States
Cancer Care Northwest Research
🇺🇸Spokane, Washington, United States
Joliet Oncology Hematology Associates
🇺🇸Joliet, Illinois, United States
Michigan Hematology and Oncology Institute
🇺🇸Southgate, Michigan, United States
Medical Oncology Associates of Wyoming Valley, PC
🇺🇸Kingston, Pennsylvania, United States
Michael McKenzie, DO
🇺🇸Clinton Township, Michigan, United States
Cancer Center of Florida
🇺🇸Ocoee, Florida, United States
Hematology Oncology Consultants
🇺🇸Royal Oak, Michigan, United States
Robert A. Moss, MD, FACP, Inc.
🇺🇸Fountain Valley, California, United States
Josephine Ford Cancer Center -- Downriver
🇺🇸Brownstown, Michigan, United States
Cancer and Transplant Consultants, PLC
🇺🇸Rochester Hills, Michigan, United States
Cancer Care Associates
🇺🇸Tulsa, Oklahoma, United States
Cancer Care Associates, PC
🇺🇸Royal Oak, Michigan, United States
Jeffrey H. Margolis, MD
🇺🇸Royal Oak, Michigan, United States
Mitchell Folbe, MD, PC
🇺🇸Troy, Michigan, United States
Oncology/Hematology Care, Inc.
🇺🇸Cincinnati, Ohio, United States
Arch Medical Services, Inc.
🇺🇸St. Louis, Missouri, United States
Texas Oncology Cancer Center--Sugar Land
🇺🇸Sugar Land, Texas, United States
Texas Cancer Center (Dallas Southwest)
🇺🇸Dallas, Texas, United States
Mary Crowley Medical Research Center
🇺🇸Dallas, Texas, United States
Texas Cancer Center / Denton
🇺🇸Denton, Texas, United States
US Oncology Research and Clinical Pharmacy
🇺🇸Ft. Worth, Texas, United States
Paris Regional Cancer Center
🇺🇸Paris, Texas, United States
West Texas Cancer Center
🇺🇸Odessa, Texas, United States
Peninsula Cancer Institute
🇺🇸Williamsburg, Virginia, United States
Jay L. Wittenkeller, MD
🇺🇸Spokane, Washington, United States
Southwest Cancer Care Medical Group
🇺🇸Poway, California, United States
Alaska Cancer Research
🇺🇸Anchorage, Alaska, United States
James P. Daugherty, MD
🇺🇸Muscle Shoals, Alabama, United States
Henry Ford Medical Center -- Fairlane
🇺🇸Dearborn, Michigan, United States
Warren Paroly, MD
🇺🇸Oceanside, California, United States
Cancer and Blood Disease Center
🇺🇸Lecanto, Florida, United States
Youssef Hanna, MD
🇺🇸Port Huron, Michigan, United States
Gabrail Cancer Center
🇺🇸Dover, Ohio, United States
Trilogy Cancer Center
🇺🇸Wooster, Ohio, United States
Dayton Hematology and Oncology
🇺🇸Kettering, Ohio, United States
Mukesh C. Bhatt, MD
🇺🇸Medina, Ohio, United States
New York Oncology Hematology, PC
🇺🇸Albany, New York, United States
George A. Zervos, MD
🇺🇸Glen Head, New York, United States
Northwestern Carolina Oncology Hematology
🇺🇸Hickory, North Carolina, United States
Chester County Hematology / Oncology Services
🇺🇸West Chester, Pennsylvania, United States
Shatish A. Shah, MD
🇺🇸Gettysburg, Pennsylvania, United States
Rittenhouse Hematology Oncology Associates
🇺🇸Philadelphia, Pennsylvania, United States
Cancer Care Institute of Carolina
🇺🇸Aiken, South Carolina, United States
Masoom Kandahari, MD, PC
🇺🇸Woodbridge, Virginia, United States
Oncology & Hematology Associates of Southwest Virginia, Inc.
🇺🇸Salem, Virginia, United States
Hematology Oncology Associates
🇺🇸Phoenix, Arizona, United States
Mile High Oncology
🇺🇸Denver, Colorado, United States
Rocky Mountain Cancer Centers
🇺🇸Denver, Colorado, United States
Henry Ford Health System
🇺🇸Detroit, Michigan, United States
Northwest Cancer Specialists, Northrup
🇺🇸Portland, Oregon, United States
Charleston Hematology Oncology, PA
🇺🇸Charleston, South Carolina, United States
Northwest Cancer Specialists, PC
🇺🇸Vancouver, Washington, United States