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Clinical Trials/NCT05244746
NCT05244746
Completed
Not Applicable

Efficacy of Ultrasound Guided Rectus Sheath Block Combined With General Anaesthesia on the Postoperative Quality of Recovery Profile in Laparotomy Surgeries, Randomized Control Trial.

Kasr El Aini Hospital1 site in 1 country48 target enrollmentMarch 1, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Postoperative Pain
Sponsor
Kasr El Aini Hospital
Enrollment
48
Locations
1
Primary Endpoint
quality of recovery
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

Effective Postoperative pain management following laparotomy represents a cornerstone in the care of surgical patients. With the growing utilization of Enhanced recovery after surgery protocols (ERAS), a paradigm shift in perioperative care has resulted in reduction of both hospital stay and clinical complications faced by patients.

One important component of successful implementation of ERAS protocol is optimized pain control. It has been shown that opioids have a considerable role in reducing bowel motility in addition; it hinders early mobilization and enteral feeding besides their commonly faced side effects such as nausea and vomiting.

Consequently, ERAS programs encourage the usage of multimodal opioid sparing analgesia which includes neuraxial or regional anesthesia techniques to provide effective pain relief while reducing the opioid related side effects. [1]

Regional blocks have remained popular with evidence of superior postoperative pain control when compared with systemic analgesics. Regional anaesthesia techniques have undergone considerable refinement with the advent of ultrasound guidance. Ultrasound visualization of anatomical structures increases both the safety and quality of regional blocks through optimal needle placement. Ultrasound-guided rectus sheath (RS) blocks are an emerging anaesthetic technique providing excellent analgesia after laparotomy. The anatomic characteristics of this block suggest minimal serious complications are likely, and this regional block is particularly useful where epidural is contraindicated

Registry
clinicaltrials.gov
Start Date
March 1, 2022
End Date
June 1, 2022
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Kasr El Aini Hospital
Responsible Party
Principal Investigator
Principal Investigator

Ayman Abougabal

A abougabal

Kasr El Aini Hospital

Eligibility Criteria

Inclusion Criteria

  • 18-60 years old patients
  • ASA 1-2 patients
  • Patients undergoing elective midline laparotomy.

Exclusion Criteria

  • refusal to consent,
  • previous laparotomy (subsequently amended to exclude only a laparotomy with a paramedian scar),
  • significant hepatic or renal disease,
  • any condition limiting the use of co-analgesics (diclofenac and acetaminophen),
  • coagulopathy (international normalized ratio: 1.5 )
  • Patients with body weight \\ 50 kg.

Outcomes

Primary Outcomes

quality of recovery

Time Frame: 24 hours

using QOR-15 questionnaire

Study Sites (1)

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