Pulmonary Hypertension in Lymphangioleiomyomatosis

Completed

• Conditions: Lymphangioleiomyomatosis; Pulmonary Hypertension

• Registration Number: NCT00960895
• Lead Sponsor: Groupe d'Etudes et de Recherche sur les Maladies Orphelines Pulmonaires

Brief Summary

This is a descriptive study of patients with Lymphangioleiomyomatosis and precapillary pulmonary hypertension.

Detailed Description

Descriptive study of patients with Lymphangioleiomyomatosis and precapillary pulmonary hypertension This will include modality of diagnosis of lLymphangioleiomyomatosis, results of right-sided heart catheterization, and pulmonary function tests

Study Timeline

• Study Start: 2009-08
• Study First Submitted: 2009-08-17
• Study First Submitted QC: 2009-08-17
• Study First Posted: 2009-08-18
• Primary Completion: 2009-12
• Study Completion: 2010-12
• Status Verified: 2011-10
• Last Update Submitted: 2011-10-26
• Last Update Posted: 2011-10-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 20

Inclusion Criteria

• Lymphangioleiomyomatosis (definite or probable), either sporadic or associated with tuberous sclerosis
• Precapillary pulmonary hypertension, as defined by right-sided heart catheterization (mean pulmonary artery pressure higher than 25 mmHg, wedge capillary pulmonary pressure less than 15 mmHg, pulmonary vascular resistance higher than 3 Wood units)

Exclusion Criteria

• Post capillary pulmonary hypertension
• Other identifiable causes of pulmonary hypertension (ex: thromboembolic disease)
• Not willing to participate

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Louis Pradel Hospital; 🇫🇷 Lyon, University of Lyon, France