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Clinical Trials/NCT05864183
NCT05864183
Recruiting
Not Applicable

Screening for Risk Factors of Prediabetes Among Adults Patients at Sohag University Hospital

Sohag University1 site in 1 country200 target enrollmentApril 15, 2023
ConditionsPreDiabetes

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
PreDiabetes
Sponsor
Sohag University
Enrollment
200
Locations
1
Primary Endpoint
comparison between the measurement of HbA1c in normal non prediabetics and prediabetics at Sohag university hospital .
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

  • Prediabetes is an intermediate state of hyperglycemia with glycemic parameters above normal but below the diabetes threshold..
  • during the average 3 years of follow-up Prediabetes is diagnosed based on laboratory tests: fasting plasma glucose level (100-125 mg/dl) ;HbA1c, (5.7-6.4%) or plasma glucose level after an oral glucose tolerance test ( 140-199 mg/dl).
  • Reports estimate that more than 470 million people will have prediabetes by 2030.
  • According to an expert panel of the American Diabetes Association, up to 70% of individuals with prediabetes will eventually develop diabetes.
  • Observational evidence suggests as association between prediabetes and complications of diabetes such early nephropathy(10%) , small fiber neuropathy(18-25 %), early retinopathy (8-12%) and risk of macrovascular disease (52%) .
  • Screening for prediabetes is designed to save lives or enhance an individual's quality of life by early detection so that screening will minimize the risk of developing diabetes or its complications .

Detailed Description

* In this case control study we aim to screen for risk factors of prediabetes among adult patients to minimize the risk of developing diabetes or its complications . * Prediabetes screening is also required to minimize medical costs such as hospitalization, outpatient care, surgery, medications, and laboratory test costs . * Several studies had shown efficacy of lifestyle interventions in diabetes prevention by targeting obesity with increase in physical activity and dietary changes with a relative risk reduction of 40%-70% in adults with prediabetes ,also there is increasing evidence to prove the efficacy of pharmacotherapy in prevention of diabetes in adults with prediabetes

Registry
clinicaltrials.gov
Start Date
April 15, 2023
End Date
December 2023
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Nermin Fathy Ezzat

internal medicine resident at faculty of medicine Sohag university

Sohag University

Eligibility Criteria

Inclusion Criteria

  • Adult patient above 18 years old .

Exclusion Criteria

  • all patients known to be diabetics .
  • pregnancy .
  • chronic depleting diseases,
  • Those who were taking drugs known to influence blood glucose levels e.g. metformin, thiazolidinedione and steroids.

Outcomes

Primary Outcomes

comparison between the measurement of HbA1c in normal non prediabetics and prediabetics at Sohag university hospital .

Time Frame: 6 months

analysis of HbA1c measurements and compare the results in both groups

Study Sites (1)

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