Effect of Oral Glucosamine on glucose and insulin levels in patients with osteoarthritis

Phase 2

• Conditions: Knee Osteoarthritis.; Polyarthrosis, unspecified

• Registration Number: IRCT201304284167N5
• Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Osteoarthritis non diabetic patients with American College Of Rheumatology criteria for diagnosis of osteoarthritis of hand, knee and or hip; patients who complete the consent form and participate to study consciously.
Exclusion criteria: Having body mass index lower than 20 and or higher than 30, history of diabetes or fast blood sugar upper than 110; history of liver or renal disease, myocardial infarction, uncontrolled inflammatory diseases, malignancy and endocrine disorder which interfere glucose metabolism; consumption of corticosteroids and other effective medicine on blood glucose; anemia; pregnancy or lactation

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Fasting blood glucose. Timepoint: Baseline and after 3 months intervention. Method of measurement: Glucose oxidase Method.;Glucose tolerance test. Timepoint: Baseline and after 3 months intervention. Method of measurement: Glucose oxidase Method.;Fasting insulin serum. Timepoint: Baseline and after 3 months intervention. Method of measurement: Immunoradiometric assay.

Secondary Outcome Measures

Name	Time	Method
Insulin Resistance. Timepoint: Baseline and after 3 months intervention. Method of measurement: HOMA-IR index.;Fasting insulin serum. Timepoint: Baseline and after 3 months intervention. Method of measurement: Immunoradiometric assay.;Fasting blood glucose. Timepoint: Baseline and after 3 months intervention. Method of measurement: Glucose oxidase Method.;Glucose tolerance test. Timepoint: Baseline and after 3 months intervention. Method of measurement: Glucose oxidase Method.