Gain of Keratinized Mucosa Around Teeth and Dental Implants Using a Combination of Strip Gingival Graft and Acellular Dermal Matrix
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Gingival Recession
- Sponsor
- University of Alabama at Birmingham
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Quality of soft tissue regenerated
- Status
- Recruiting
- Last Updated
- 9 months ago
Overview
Brief Summary
This study is to compare the two techniques to achieve change in the tissue quality at areas of lack of Keratinized Tissue (KT) using soft tissue grafting with autogenous graft material (Free Gingival Graft)(FGG) vs Strip gingival graft with acellular dermal matrix (ADM) (SGG+ADM).
Detailed Description
This investigation is a randomized controlled trial of two techniques to achieve change in the tissue quality at areas of lack of Keratinized Tissue (KT) using soft tissue grafting with autogenous graft material (Free Gingival Graft)(FGG) vs Strip gingival graft with acellular dermal matrix (ADM) (SGG+ADM). To evaluate to determine if either grafting technique (FGG vs SGG+ADM) demonstrates superiority in clinical (amount of KT increase, tissue thickness increase, and practitioner-assessed esthetics) and patient-centered outcomes (pain, swelling, change in daily activities, and patient-assessed esthetics) in a controlled study.
Investigators
Hussein Basma
Principal Investigator
University of Alabama at Birmingham
Eligibility Criteria
Inclusion Criteria
- •English speaking
- •At least 18 years old
- •Able to read and understand informed consent document
- •Patients with teeth/implants lacking keratinized tissue.
- •Must be a patient of the UAB Dental School
- •Presence of periodontally healthy, non-carious neighboring teeth, healthy implants or edentulous ridges on either side of the involved site(s)
Exclusion Criteria
- •Non-English speaking
- •Less than 18 years old
- •Smokers/tobacco users (\>10 cigarettes/day)
- •Patients with systemic pathologies or conditions contraindicating oral surgical procedures or adversely affecting wound healing
- •Presence of active periodontal disease
- •Previous soft tissue grafting at the site(s) to be treated
Outcomes
Primary Outcomes
Quality of soft tissue regenerated
Time Frame: From baseline to 12 months
Compare the change in soft tissue quality (attached or keratinized ) between two used soft tissue grafts by superimposing the before and after intraoral scans and the calculating using a software the difference of soft tissue gain between both scans in (mm)
Quantity of soft tissue regenerated (Width of Keratinized Tissue)
Time Frame: From baseline to 12 months
Using a periodontal probe , the width of keratinized tissue will be measured in (mm) and compared between two grafts used.