Brain Imaging Study of Amyotrophic Lateral Sclerosis Based on Accurate Brain Volume Quantitative Analysis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Amyotrophic Lateral Sclerosis
- Sponsor
- Peking University Third Hospital
- Enrollment
- 32
- Locations
- 1
- Primary Endpoint
- Accurate quantitative analysis of brain volume
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
Using the original MRI images of 16 ALS patients and 16 normal controls matched by gender, age and education level in the previous study, the differences of brain volume in different parts of ALS patients and normal controls, and the correlation between brain structure and clinical characteristics were compared by precise brain volume quantitative analysis technology.
Detailed Description
This study was a retrospective study. The subjects were 16 ALS patients and 16 normal controls. Previous studies have collected patients' age, gender and education level; The onset site, onset time, bulbar involvement, diagnostic grade, ALSFRS-R score, application of ventilator, application of lirutai, gastrostomy; Age, gender and education level were collected in the control group. Accurate quantitative analysis of brain volume was performed on the original brain MRI images of the two groups.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Diagnosed ALS patients
- •healthy volunteers
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Accurate quantitative analysis of brain volume
Time Frame: 1 day
Accurate quantitative analysis of brain volume using magnetic resonance brain imaging
Secondary Outcomes
- general situation(1 day)