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临床试验/NCT05338593
NCT05338593已完成不适用

Therapy and Outcome of Prolonged Veno-venous ECMO Therapy of Critically Ill ARDS Patients.

Goethe University1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2022年5月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
100
试验地点
1
主要终点
Mortality

研究概览

简要总结

In the context of the coronavirus (COVID-19) pandemic, healthcare systems worldwide faced an unprecedented shortage of severe ARDS. Critically affected patients were treated with veno-venous extracorporeal membrane oxygenation (VV-ECMO) for complete respiratory failure early in the pandemic. Due to a shortage of resources in the sense of terminal equipment and adequately trained personnel with appropriate expertise in many countries and regions, a strict selection of suitable patients was made. Repeatedly, it was observed that patients under VV-ECMO also needed several weeks to recover sufficiently to generate device sufficient gas exchange. Due to the scarcity of VV-ECMO resources outside of the pandemic, the question arose whether a prolonged therapy still holds a sufficient prospect of success and what the course of treatment of such patients would be like.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • veno-venous extracorporeal membrane oxygenation

排除标准

  • veno-arterial extracorporeal membrane oxygenation

结局指标

主要结局

Mortality

时间窗: During intensive care treatment (Usually within 25 weeks)

Mortality rate under ongoing veno-venous extracorporeal membrane oxygenation over time

次要结局

  • Major bleeding(During intensive care treatment (Usually within 25 weeks))
  • critical device error(During intensive care treatment (Usually within 25 weeks))

研究者

发起方
Goethe University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Armin N. Flinspach

Principal Investigator

Goethe University

研究点 (1)

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