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Clinical Trials/CTRI/2024/06/068711
CTRI/2024/06/068711
Completed
Phase 2

An open labelled non-randomized phaseII clinical trial to evaluate the effectiveness of Mezhugu kalimbu(External therapy)in the management of Narambu kiranthi (varicose Ulcer)

Dr DHINAKARAN T1 site in 1 country40 target enrollmentStarted: June 26, 2024Last updated:

Overview

Phase
Phase 2
Status
Completed
Sponsor
Dr DHINAKARAN T
Enrollment
40
Locations
1
Primary Endpoint
The outcome of the study will be assessed by reduction in the margins(size) of the wound and better healing.

Overview

Brief Summary

This study is an open labelled non randomised phase II  clinical trial to evaluate the effectiveness of MEZHUGU KALIMBU ( external therapy) in the management of NARAMBU KIRANTHI( varicose ulcer).This trial drug will be  an external application for daily 15 days in  40 patients.The trial period of 24 moths will be carried out in government Siddha medical College and hospital, palayamkottai, Tirunelveli 627002, Tamilnadu,The outcome of the study will be assessed by reduction in the margins(size) of the wound and better healing.In clase of any adverse events is noticed and it will be referred to pharmacovigilence department,and further management of patients will be given OPD patients.

Study Design

Study Type
Interventional
Allocation
Na
Masking
None

Eligibility Criteria

Ages
40.00 Year(s) to 70.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Patient who are willing to take external therapy alone Patient who are willing for admission and stay in IPD or willing to attend OPD.
  • Patients who are willing to give blood samples for laboratory investigations.

Exclusion Criteria

  • Pregnant and lactating women Severe renal, hepatic, cardiac disease Malignant ulcers Uncontrolled diabetes Syphilitic ulcers Ischemic ulcers Traumatic ulcers.

Outcomes

Primary Outcomes

The outcome of the study will be assessed by reduction in the margins(size) of the wound and better healing.

Time Frame: 15 days

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Dr DHINAKARAN T
Sponsor Class
Other [self]
Responsible Party
Principal Investigator
Principal Investigator

DHINAKARAN T

Government siddha medical College and hospital, palayamkottai

Study Sites (1)

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