Relationship between Vertebral fracture assessment and bone mineral density among postmenopausal women with ankle fracture

Phase 4

Completed

• Conditions: Fragility fracture; Postmenopausal women, fragility fracture, bone mineral density, Vertebral fracture assessment, ankle fracture

• Registration Number: TCTR20230214004
• Lead Sponsor: Police General Hospital

Brief Summary

In this study, Total spinal BMD, Interochanter BMD, and TBS are tools that early detect osteoporosis in postmenopausal women with low energy trauma ankle fractures earlier than total hip BMD. In practice, VFA and TBS investigation may be informative to guide in the treatment of postmenopausal patients diagnosed with a non-fatal ankle fracture in the future.

Detailed Description

Not available

Study Timeline

• Study Completion: 2022-07-29
• Study Start: 2023-02-14
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 40

Inclusion Criteria

1. Postmenopausal women aged 50 years and over with a low energy traumatic ankle fracture after menopausal period.
2. Postmenopausal women aged 50 years and over with low energy traumatic fractures forearm, wrist, hip, spine either or those diagnosed with osteoporosis.

Exclusion Criteria

1. Patients who are unable to entry Dual X-ray absorptiometry
2. Patients with medical equipment including any foreign matter at the point of investigation
3. There is a marked erosion or deformity at the measured site
4. Those who had total Hysterectomy with bilateral salpingo-oophorectomy before menopause
5. Estrogen deficiency before entering menopause for more than 1 year
6. Patients had taking glucocorticoids for more than 3 months.
7. Patients with rheumatoid arthritis

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bone mineral density At the beginning of study Dual X-ray absorptiometry,Vertebral fracture assessment At the beginning of study Dual X-ray absorptiometry,Trabecular bone score At the beginning of study Dual X-ray absorptiometry

Secondary Outcome Measures

Name	Time	Method
Bone mineral density in subgroup At the beginning of study Dual X-ray absorptiometry,Vertebral fracture assessment in subgroup At the beginning of study Dual X-ray absorptiometry