MRI study to prepare for adaptive MRI-guided radiation of prostate carcinoma
- Conditions
- prostate carcinoma
- Registration Number
- NL-OMON20274
- Lead Sponsor
- Radiotherapiegroep
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 10
In order to be eligible to participate in this study, a subject must meet all of the following criteria:
•Patients with a low to intermediate risk localized PCa confirmed by biopsy and scheduled for curative intent EBRT at RTG;
•= 18 years;
•No transurethral resection of the prostate (TURP) in the last 3 months;
•No anorectal surgery in the past or other situations in which the anorectal anatomy is abnormal;
•No hip prosthesis;
•Meet all MRI safety criteria for MRI at 1.5T according to the protocol of the department of Radiology;
•Written informed consent.
•V18 years;
•Transurethral resection of the prostate (TURP) in the last 3 months;
•Anorectal surgery in the past or other situations in which the anorectal anatomy is abnormal;
•Hip prosthesis;
•No compliance with all MRI safety criteria for MRI at 1.5T according to the protocol of the department of Radiology;
•No written informed consent.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method oD2cc of the rectum (the minimum dose in 2cc of the rectum receiving the highest dose) and the mean difference in D2cc between the traditional and the online adaptive protocol. <br>oD2cc of the bladder (the minimum dose in 2cc of the bladder receiving the highest dose) and the mean difference in D2cc between the traditional and the online adaptive protocol.
- Secondary Outcome Measures
Name Time Method oD99% and D95% CTV prostate<br>oD50% of the rectum and bladder<br>oDmean of the anal canal<br>oD2cc of the small bowel <br>Dx% is the minimum dose to the highest irradiated x% volume of the volume of interest.