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Comparison of two types of intraocular lenses meant for providing both distance and near vision after cataract surgery

Phase 3
Conditions
Health Condition 1: H259- Unspecified age-related cataract
Registration Number
CTRI/2023/12/060492
Lead Sponsor
Biotech Vision Care Pvt Ltd Ahmedabad India
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. Cataractous lens changes as demonstrated by best corrected

visual acuity of 20/40 or worse either with or without a glare

source present (e.g., Brightness Acuity Tester) or with significant

cataract-related visual symptoms.

2. Best corrected visual acuity to be better than 20/30 after cataract

removal and IOL implantation as estimated by potential acuity

meter (PAM) or surgeon estimation

3. Clear intraocular media other than cataract.

4. Given written informed consent by subject.

5. Subjects are willing and able to comply with schedule for follow up visits.

6. Subjects should be 22 years or older.

Exclusion Criteria

1. Systemic disease that could increase the operative risk or

confound the outcome.

2. Systemic medications that may confound the outcome or increase

the risk to the subject in the opinion of the investigator

(tamsulosin hydrochloride (Flomax) or other medications with

similar side effects (floppy iris syndrome)).

3. Ocular condition that may predispose for future complications.

4. Previous intraocular or corneal surgery that might confound the

outcome of the investigation or increase the risk to the subject.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Binocular Distance Corrected Intermediate Visual Acuity at <br/ ><br>66cm (DCIVA@66cm) under photopic light conditionsTimepoint: Pre-operative, 1-2days, 7-14 days, 30-60 days, 120-180 days, 330- <br/ ><br>420 days]
Secondary Outcome Measures
NameTimeMethod
1) Uncorrected distance visual acuity (UCDVA) [photopic] <br/ ><br>2) Uncorrected intermediate visual acuity (UCIVA) [photopic] <br/ ><br>3) Best corrected distance visual acuity (BCDVA) [photopic] <br/ ><br>4) Uncorrected Near visual acuity (UCNVA) [photopic] <br/ ><br>5) Distance corrected Near visual acuity (DCNVA) [photopic] <br/ ><br>6) Distance-corrected intermediate visual acuity (DCIVA) <br/ ><br>[photopic] <br/ ><br>7) Low Contrast (10%) Distance Corrected Intermediate Visual <br/ ><br>Acuity [photopic] <br/ ><br>8) Low Contrast (10%) Best Corrected Intermediate Visual Acuity <br/ ><br>[photopic] <br/ ><br>9) Defocus curves monocular and binocular <br/ ><br>10) Manifest refraction <br/ ><br>11) Subject questionnaire <br/ ><br>12) Subject ocular and visual symptoms (non-directed questions) <br/ ><br>13) Rotational stability <br/ ><br>14) Spherical equivalent <br/ ><br>Timepoint: Pre-operative, 1-2days, 7-14 days, 30-60 days, 120-180 days, 330- <br/ ><br>420 days]
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