Secondary Prevention of Small Subcortical Vascular Brain Attacks

FUNDACION CAYETANO HEREDIA,0 个研究点目标入组 186 人开始时间: 2006年2月7日最近更新: 2023年9月4日

适应症

试验速览

暂无简介。

•1. One of the lacunary syndromes adapted by Fisher and lasting more than 24 hours.
•2. Absence of signs of cortical dysfunction.
•3. If the S3 is hemispherical, there should not be ipsilateral carotid stenosis> 50%.
•4. Patients with high-risk cardioembolic sources requiring anticoagulation will not be included.
•5. Evidence of: A) S3 in MRI B) Absence of cortical ACV and extensive subcortical ACV (> 1.5 cm), both recent and remote.

•1- Disabling ACV.
•2- Previous intracranial hemorrhage or hemorrhagic stroke.
•3- Age under 40 years.
•4- Patients with a high risk of bleeding.
•5- Patients possibly requiring anticoagulant treatment or with other antiplatelet agents in the future.
•6- Previous cortical ACV.
•7- Previous ipsilateral carotid endarterectomy.
•8- Alteration in renal function.
•9- Intolerance or contraindication to the use of aspirin or clopidogrel.
•10-A score <24 in the Minimental of Folstein.
•11-Medical contraindication for the realization of the RNM.
•12-Pregnancy or women of childbearing age who do not follow effective contraceptive treatment.
•13-Social or geographical factors that make it difficult to participate in the study.
•14-Patients incapacitated or who do not want to sign the consent of the study.
•15-Patients who do not comply with the treatment or who want to return to frequent controls.
•16-Simultaneous participation with other research protocols.
•17-Other possible mechanisms of stroke.

发起方

FUNDACION CAYETANO HEREDIA,