Chemically assisted endoscopic submucosal dissection by using mesna for esophageal cancer.
Not Applicable
Completed
- Conditions
- Superficial esophageal squamous cell carcinoma
- Registration Number
- JPRN-UMIN000007238
- Lead Sponsor
- The Jikei University School of Medicine, Department of Endsocopy
- Brief Summary
An en bloc resection rate was 100%. The mechanical submucosal dissection with mesna for surperficial esophageal neoplasms deem safe and may facilitate procedure of conventional ESD.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
Patients with allergic history to mesna
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method En bloc resection rate
- Secondary Outcome Measures
Name Time Method Short and long term complication, duration of procedure, number of coagularion for bleeding
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie mesna's role in chemically assisted endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma?
How does chemically assisted ESD with mesna compare to conventional ESD in terms of en bloc resection rates and complication profiles for early esophageal cancer?
Are there specific biomarkers that could identify patients with superficial esophageal neoplasms who may benefit most from mesna-assisted endoscopic submucosal dissection?
What are the potential adverse events associated with mesna use in endoscopic submucosal dissection procedures and how can they be managed?
What other chemically assisted endoscopic techniques or compounds are being explored for esophageal cancer resection alongside or as alternatives to mesna?