Beneficial Effects of Microsurgical Varicocelectomy on Semen Parameters in Patients Who Underwent Surgery for Causes Other Than Infertility
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 121
- Locations
- 1
- Primary Endpoint
- Sperm concentration, motility, and morphology
Study Overview
Brief Summary
The purpose of this study is to evaluate whether clinical varicoceles are associated with abnormal semen parameters and whether varicocelectomy could improve the semen parameter in patients unrelated with infertility.
Detailed Description
While most studies are continued to validate the observations of significant improvements in sperm density and motility after varicocele ligation in infertile patients, there have been few studies to investigate the effects of varicocelectomy on semen parameters in adult men unrelated with infertility. The purpose of this study was to determine whether varicocelectomy could improve the semen parameter of these patients as well as whether clinical varicoceles are associated with abnormal semen parameters in patients unrelated with infertility.
Study Design
- Study Type
- Observational
- Observational Model
- Case Only
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 20 Years to 45 Years (Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •men with clinical varicoceles underwent microsurgical varicocelectomy due to causes other than infertility such as testicular pain, discomfort or scrotal mass
Exclusion Criteria
- •adolescents
- •men with proven fertility or azoospermia
- •men with preoperative normal sperm analysis
- •available data to compare between preoperative and postoperative semen analyses
Outcomes
Primary Outcomes
Sperm concentration, motility, and morphology
Time Frame: at postoperative 4months
To observe the change of sperm concentration, motility, and morphology pre and postoperatively in the patients of inclusion criteria
Secondary Outcomes
- whether semen analysis should be done in men with clinical varicocele regardless of the chief complaint(at postoperative 4months)
Investigators
Soo Woong Kim, MD
Professor
Seoul National University Hospital