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Comparison of Bone Graft and Photodynamic Therapy in Class II Furcation

Not Applicable
Completed
Conditions
Furcation Defects
Registration Number
NCT06519409
Lead Sponsor
Krishnadevaraya College of Dental Sciences & Hospital
Brief Summary

This is a surgical comparative clinical trial which aims to assess class II buccal furcation defects treated with Xenograft alone or preceded by antimicrobial photodynamic therapy.

Detailed Description

To test the efficacy of photodynamic therapy (Indocyanine green) along with placement of xenograft (Cerabone®-Natural bovine bone grafting material, Botiss biomaterials) to treat a class II furcation defects. The topical study was designed as a randomized controlled, single blinded (patient), split mouth clinical trial with 14 participants. In the control group, the defects were filled with xenograft (Cerabone®) whereas the test group received photodynamic therapy (Indocyanine green) in addition to grafting. Radiovisiography technique was used to observe the possible changes in the furcation region at baseline and 9 months postoperatively.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
14
Inclusion Criteria

Systemically healthy subjects Age group of 25-60 years Presence of class II furcation defect on buccal surfaces of mandibular molars as determined by clinical and radiographic evaluation.

Vertical probing depth (VPD) ≥4mm Horizontal probing depth (HPD) ≥4 mm Gingival margin (GM) coronal to or at the level of the roof of the furcation

Exclusion Criteria

Current and former smokers Administration of antibiotics in the last 6 months History of any periodontal therapy in the past 6 months Known allergic responses to bovine derived graft materials and photosensitizers.

Pregnant and lactating women.

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
percentage of bone fill9 months

amount of bone formation

Secondary Outcome Measures
NameTimeMethod
Clinical efficacy9 months

clinical attachment level

Trial Locations

Locations (1)

Dr. Prabhuji MLV

🇮🇳

Bengaluru, Karnataka, India

Dr. Prabhuji MLV
🇮🇳Bengaluru, Karnataka, India

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