Comparison of Bone Graft and Photodynamic Therapy in Class II Furcation
- Conditions
- Furcation Defects
- Registration Number
- NCT06519409
- Lead Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
- Brief Summary
This is a surgical comparative clinical trial which aims to assess class II buccal furcation defects treated with Xenograft alone or preceded by antimicrobial photodynamic therapy.
- Detailed Description
To test the efficacy of photodynamic therapy (Indocyanine green) along with placement of xenograft (Cerabone®-Natural bovine bone grafting material, Botiss biomaterials) to treat a class II furcation defects. The topical study was designed as a randomized controlled, single blinded (patient), split mouth clinical trial with 14 participants. In the control group, the defects were filled with xenograft (Cerabone®) whereas the test group received photodynamic therapy (Indocyanine green) in addition to grafting. Radiovisiography technique was used to observe the possible changes in the furcation region at baseline and 9 months postoperatively.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 14
Systemically healthy subjects Age group of 25-60 years Presence of class II furcation defect on buccal surfaces of mandibular molars as determined by clinical and radiographic evaluation.
Vertical probing depth (VPD) ≥4mm Horizontal probing depth (HPD) ≥4 mm Gingival margin (GM) coronal to or at the level of the roof of the furcation
Current and former smokers Administration of antibiotics in the last 6 months History of any periodontal therapy in the past 6 months Known allergic responses to bovine derived graft materials and photosensitizers.
Pregnant and lactating women.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method percentage of bone fill 9 months amount of bone formation
- Secondary Outcome Measures
Name Time Method Clinical efficacy 9 months clinical attachment level
Trial Locations
- Locations (1)
Dr. Prabhuji MLV
🇮🇳Bengaluru, Karnataka, India
Dr. Prabhuji MLV🇮🇳Bengaluru, Karnataka, India