SIOPEL 5 (HCC-1) trial on the hepatocellular carcinoma family of tumours in children/adolescents and young adults - SIOPEL 5

K Children’s Cancer Study Group0 个研究点目标入组 47 人开始时间: 2005年3月22日最近更新: 2020年7月27日

适应症

试验速览

暂无简介。

•Newly diagnosed non-cirrhotic hepatocellular carcinomasq
•<30 years of age at the time of diagnosisq
•No previous treatment for HCC
•Appropriate diagnostic / staging imaging performed.
•Confirmed diagnosis - hepatocellular carcinoma family” of tumours: includes fibrolamellar and transitional variants. (NB: percutaneous needle biopsy is mandatory, unless primary tumour resection is attempted)
•Negative pregnancy test
•Written informed consent and national/local ethical committee approval
•Are the trial subjects under 18? yes
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range

•Patients unable to follow the protocol for any reason
•Patients referred for recurrent disease
•Positive pregnancy test
•Patients with life expectancy below 3 months
•Abnormal renal function at diagnosis as GFR <75-50% of the lower limit of normal for age which over 2 years of age is <60ml/min/1.73m2
•Cardiac EF <29% at baseline echo

发起方

K Children’s Cancer Study Group