Oxycodone Concentration in the Blood After Oral Premedication
- Registration Number
- NCT03386318
- Lead Sponsor
- Sahlgrenska University Hospital, Sweden
- Brief Summary
Oxycodone is an opioid frequently given orally as a premedication prior to any kind of surgery. The initial studies are performed on healthy testpersons and is not given in surgery. The investigators want to explore serum concentration over time (5h) and relate this to Visual Analoge Scale (VAS) postoperatively but also to given mg/kg
- Detailed Description
Oxycodone is an opioid frequently given orally as a premedication prior to any kind of surgery. The initial studies are performed on healthy test-persons and is not given in surgery. The investigators want to explore serum concentration over time (5h) and relate this to Visual Analoge Scale (VAS) postoperatively but also to given mg/kg 20 female patients between 30 and 60 years will be included after informed consent. They will have day-surgery. The patients will receive 5 mg oxycodone if weighing less than 60 kg and 10 mg if weighing over 60 kg. Serum samples will be taken 1, 2,3,4, and 5 hours after medication intake and serum concentrations will be analyzed
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 20
- Females <100kg, non-opioid tolerant, day surgery and informed consent
- In complying to inclusion criterias
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description day surgery patients Oxycodone 20 patients female 30-60 years of age
- Primary Outcome Measures
Name Time Method Oxycodone concentration in the blood after oral premedication 2 days Concentration study
Oxycodone concentrations and pain after oral premedication 7 day Visual analoge Scale
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Sahlgrenska UH
🇸🇪Mölndal, Västra Götaland, Sweden