Predictive Value of Combining AccuIMR and AccuFFR in Patients With STEMI

Active, not recruiting

• Conditions: Prognosis; Acute ST Segment Elevation Myocardial Infarction
• Interventions: Diagnostic Test: AccuIMR and AccuFFR

• Registration Number: NCT06435728
• Lead Sponsor: Peking University Third Hospital

Brief Summary

Patients with acute myocardial infarction were enrolled retrospectively. The fractional flow reserve (AccuFFR) and microcirculatory resistance index (AccuIMR) based on coronary angiography were analyzed, and the relationship between FFR and IMR and the prognosis of patients with acute myocardial infarction was analyzed

Detailed Description

We retrospectively enrolled STEMI patients who underwent PCI in Peking University Third Hospital. The fractional flow reserve (AccuFFR) and microcirculatory resistance index (AccuIMR) based on coronary angiography were obtained by analyzing the coronary angiography images. The prognosis of patients was obtained by searching inpatient and outpatient systems and telephone follow-up. The relationship between AccuFFR, AccuIMR and prognosis was statistically analyzed

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2024-03-01
• Primary Completion: 2024-04-30
• Status Verified: 2024-05
• Study First Submitted: 2024-05-26
• Study First Submitted QC: 2024-05-26
• Last Update Submitted: 2024-05-26
• Study Completion: 2024-05-30
• Study First Posted: 2024-05-30
• Last Update Posted: 2024-05-30

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 1297

Inclusion Criteria

• Age of >18 years;
• Onset-to-treatment time of ≤12 h, meeting the diagnostic criteria for STEMI;
• underwent primary PCI within 12 h of symptom onset and achieved successful PCI in the culprit vessel;
• Availability of complete clinical data

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Exclusion Criteria

• severe tortuosity and overlap of the target vessel;
• poor-quality coronary angiography images;
• missing two coronary angiography images >25° apart

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
STEMI	AccuIMR and AccuFFR	Patients with STEMI who underwent primary PCI and were hospitalized at Peking University Third Hospital between January 2017 and March 2022

Primary Outcome Measures

Name	Time	Method
MACE	3 years after myocardial infarction	cardiovascular death, all-cause death, readmission for heart failure (HF), and recurrent coronary events

Secondary Outcome Measures

Name	Time	Method
recurrent coronary events	3 years after myocardial infarction	nonfatal myocardial infarction, unplanned PCI, and unplanned coronary artery bypass grafting

Trial Locations

Locations (1)

Peking University Third Hospital; 🇨🇳 Beijing, China