Predictive Value of Combining Angio-Based Index of Microcirculatory Resistance and Fractional Flow Reserve in Patients With STEMI
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 1,297
- 试验地点
- 1
- 主要终点
- MACE
研究概览
简要总结
Patients with acute myocardial infarction were enrolled retrospectively. The fractional flow reserve (AccuFFR) and microcirculatory resistance index (AccuIMR) based on coronary angiography were analyzed, and the relationship between FFR and IMR and the prognosis of patients with acute myocardial infarction was analyzed
详细描述
We retrospectively enrolled STEMI patients who underwent PCI in Peking University Third Hospital. The fractional flow reserve (AccuFFR) and microcirculatory resistance index (AccuIMR) based on coronary angiography were obtained by analyzing the coronary angiography images. The prognosis of patients was obtained by searching inpatient and outpatient systems and telephone follow-up. The relationship between AccuFFR, AccuIMR and prognosis was statistically analyzed
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age of >18 years;
- •Onset-to-treatment time of ≤12 h, meeting the diagnostic criteria for STEMI;
- •underwent primary PCI within 12 h of symptom onset and achieved successful PCI in the culprit vessel;
- •Availability of complete clinical data
排除标准
- •severe tortuosity and overlap of the target vessel;
- •poor-quality coronary angiography images;
- •missing two coronary angiography images >25° apart
结局指标
主要结局
MACE
时间窗: 3 years after myocardial infarction
cardiovascular death, all-cause death, readmission for heart failure (HF), and recurrent coronary events
次要结局
- recurrent coronary events(3 years after myocardial infarction)