NCT02855554RecruitingNot Applicable
Novel Magnetic Resonance Imaging Techniques for Quantitative Cardiac Parametric Mapping
Medical University of South Carolina2 sites in 1 country240 target enrollmentStarted: June 20, 2014Last updated:
Conditions
Interventions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Enrollment
- 240
- Locations
- 2
- Primary Endpoint
- Clinical value of fast T1, T2, and T2* mapping of the left ventricle for the assessment of necrosis/scar, edema, and possible intramyocardial hemorrhage in patients with heart disease.
Study Overview
Brief Summary
The overall goal of this project is to evaluate the clinical potential of fast quantitative myocardial tissue characterization using recently emerged Cardiac Magnetic Resonance Imaging (CMR) techniques to aid the diagnosis, treatment, and follow up of patients with myocardial diseases, such as ischemic heart disease, cardiomyopathies, and myocarditis.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Diagnostic
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 90 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Subject must be 18-90 years of age.
- •Subject must be previously diagnosed with or suspected to have one of the following conditions.
- •Myocardial ischemia or infarction (group 1)
- •Hypertrophic cardiomyopathy (group 2)
- •Infiltrative cardiomyopathy (group 3)
- •Myocarditis (group 4)
- •Subject must have been referred for a clinically indicated CMR.
Exclusion Criteria
- •Subject has any implanted device or condition in which an MR scan would be contraindicated.
- •Subject has an acute psychiatric disorder or is cognitively impaired.
- •Subject is using or is dependent on substances of abuse.
- •Subject is unwilling to comply with the requirements of the protocol.
- •Subject has previously entered this study.
- •Subject has an allergy against MRI contrast agents.
- •Subject is in acute unstable condition.
Arms & Interventions
Additional 5 minute research MR scan of heart.
Experimental
The purpose of this is to evaluate new, faster MR scans
Intervention: Cardiac Magnetic Resonance (CMR) imaging techniques (Other)
Outcomes
Primary Outcomes
Clinical value of fast T1, T2, and T2* mapping of the left ventricle for the assessment of necrosis/scar, edema, and possible intramyocardial hemorrhage in patients with heart disease.
Time Frame: 2 years
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (2)
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