Evaluating the Efficacy of Current Treatments for Reducing Postoperative Ileus

Not Applicable

Completed

• Conditions: Post-operative Ileus
• Interventions: Dietary Supplement: olive oil; Dietary Supplement: olive oil and chewing gum; Dietary Supplement: chewing gum; Dietary Supplement: water

• Registration Number: NCT01869231
• Lead Sponsor: Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo

Brief Summary

Aim was to investigate efficacy of current treatments - water, chewing gum, and olive oil, in resolving postoperative ileus.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-04
• Primary Completion: 2012-12
• Status Verified: 2013-05
• Study First Submitted: 2013-05-27
• Study First Submitted QC: 2013-06-04
• Last Update Submitted: 2013-06-04
• Study First Posted: 2013-06-05
• Last Update Posted: 2013-06-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 360

Inclusion Criteria

• Patients underwent abdominal surgery for non neoplastic diseases

Exclusion Criteria

• Metastatic disease
• History of inflammatory bowel disease
• Postoperative fever
• Gastrointestinal fistula
• Mint or olive allergy; and/or
• Earlier abdominal radiation

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
ileostomy and colostomy	water	ileostomy colostomy
ileostomy and colostomy	chewing gum	ileostomy colostomy
ileostomy and colostomy	olive oil and chewing gum	ileostomy colostomy
major surgery	olive oil	colic surgery
major surgery	olive oil and chewing gum	colic surgery
major surgery	chewing gum	colic surgery
major surgery	water	colic surgery
minor surgery	olive oil	appendectomy; cholecystectomy
minor surgery	olive oil and chewing gum	appendectomy; cholecystectomy
minor surgery	chewing gum	appendectomy; cholecystectomy
minor surgery	water	appendectomy; cholecystectomy
ileostomy and colostomy	olive oil	ileostomy colostomy
other surgery	olive oil	all of others abdominal surgical intervention
other surgery	olive oil and chewing gum	all of others abdominal surgical intervention
other surgery	chewing gum	all of others abdominal surgical intervention
other surgery	water	all of others abdominal surgical intervention

Primary Outcome Measures

Name	Time	Method
time to flatus	two days

Secondary Outcome Measures

Name	Time	Method
time to stool	five days

Trial Locations

Locations (1)

Università di palermo; 🇮🇹 Palermo, Italy