Evaluation of a clinical decontamination protocol
Completed
- Conditions
- Exposure to toxic materialsInjury, Occupational Diseases, Poisoning
- Registration Number
- ISRCTN61073828
- Lead Sponsor
- Intertox Ltd
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 18
Inclusion Criteria
1. Volunteers
2. Male or female
3. Age 18 – 60 (at the start of the study)
Exclusion Criteria
1. Allergy to aspirin
2. Currently taking blood-thinning agents (anti-coagulant or anti-platelet)
3. Renal impairment
4. Inflammatory disorder affecting the skin
5. Partially healed/open wounds
6. Respiratory condition (other than controlled asthma)
7. Pregnant or breastfeeding
8. Any other relevant condition at the discretion of an independent physician
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The effectiveness of the protocol, determined by LC-DAD-MS measurements of the amount of a chemical contaminant (curcumin/methyl salicylate mixture) recovered from the hair and skin of exposed participants in comparison with a control (exposed, untreated) treatment group
- Secondary Outcome Measures
Name Time Method Semi-quantitative determination of the area of contamination on hair and skin surfaces, observed by fluorescent imaging of exposed participants in comparison with a control (exposed, untreated) treatment group