To study the effect of NIMBAPANCHAKA CHURNA in the management of Purishaja Krimi (Helminthic Infestation )in children.

Phase 3

Not yet recruiting

• Conditions: Ascariasis, unspecified. Ayurveda Condition: PURISHAJAKRUMIH,

• Registration Number: CTRI/2024/10/076015
• Lead Sponsor: Bhagyashree Jagdish Nawlani

Brief Summary

Helminthiasis is the most common paediatric complaint world wide. Most of the world’s population is infected with one of the most common parasites like thread worms, round worms, hook worms, tape worms. The complaints towards the infestation of intestinal worms come with greater incidence in paediatric practice.

Use of uncovered food or improper washing of food materials, poverty, ignorance, lack of hygiene maintenance, bad sanitation etc. are the important factors for spreading helminthic infection in developing countries like India.

Charak, Sushruta, Vagbhata, Madhavnidana, Sharangdhara,Yogratnakar, Bhavprakasha, etc. have given wide description about krimi.

Total 20 krimis are mentioned and are classified as:-

A) Bahya

B) Abhyantara krimi.

Abhyantar krimi further divided into 3 types:-

A) Kaphaja

B) Raktajka

C) Purishaja krimi.

Chikitsa has been evolved in krimiroga in contex viz:-

A) Apakarshana

B) Prakritivighataka

C) Nidan parivarjana.

In Ayurveda many krimighna drugs are mentioned. In this regard ‘Nimbapanchaka Churna’, having krimighna property mentioned in “Yogaratnakara†( shloka -04 in Krimirog chikitsa Adhyaya) is selected.

All that drugs possess properties mentioned for krimighna drugs.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-10-11
• Last Update Posted: 2024-10-23

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

1. Patientsirrespective of their gender, religion, & socioeconomic status 2)patients exhibiting symptoms of purishaja krimi mentioned in texts like udarshool, agnimandya, panduta, gudakandu.

Exclusion Criteria

• 1)Patients below age 3 and above 12 year.
• 2)Patients presenting with complications occurred due to nematodes infestation 3)Any other systemic diseases which interfere with long term treatment.
• 4)Patient requiring surgical intervention.
• 5)Patient with symptoms like Abdominal pain affecting daily activities, Whitish pallor with skin pigmentation, Anal itching with disturbance of activity &sleep.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Udarshool (Abdominal pain)	Baseline- 7th, 14th day
Panduta (Pallor)	Baseline- 7th, 14th day
Agnimandya(Loss Of Apetite)	Baseline- 7th, 14th day
Gudakandu (Anal Itching)	Baseline- 7th, 14th day

Secondary Outcome Measures

Name	Time	Method
Panduta (Pallor)	Agnimandya(Loss Of Apetite)

Trial Locations

Locations (1)

Chatrapati Shahu Maharaj Shikshan Sansthas Ayurveda Mahavidyalaya and Rugnalaya; 🇮🇳 Aurangabad, MAHARASHTRA, India

Chatrapati Shahu Maharaj Shikshan Sansthas Ayurveda Mahavidyalaya and Rugnalaya

🇮🇳Aurangabad, MAHARASHTRA, India

Dr Bhagyashree Jagdish Nawlani

Principal investigator

09175046111

nawlanibhagyashree@gmail.com