Randomized Controlled Clinical Study to Evaluate the Efficacy of NIMBAPANCHAKA CHURNA in the management of Purishaja Krimi in children w.s.r. to Ascaris lumbricoides.
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Udarshool (Abdominal pain)
研究概览
简要总结
Helminthiasis is the most common paediatric complaint world wide. Most of the world’s population is infected with one of the most common parasites like thread worms, round worms, hook worms, tape worms. The complaints towards the infestation of intestinal worms come with greater incidence in paediatric practice.
Use of uncovered food or improper washing of food materials, poverty, ignorance, lack of hygiene maintenance, bad sanitation etc. are the important factors for spreading helminthic infection in developing countries like India.
Charak, Sushruta, Vagbhata, Madhavnidana, Sharangdhara,Yogratnakar, Bhavprakasha, etc. have given wide description about krimi.
Total 20 krimis are mentioned and are classified as:-
A) Bahya
B) Abhyantara krimi.
Abhyantar krimi further divided into 3 types:-
A) Kaphaja
B) Raktajka
C) Purishaja krimi.
Chikitsa has been evolved in krimiroga in contex viz:-
A) Apakarshana
B) Prakritivighataka
C) Nidan parivarjana.
In Ayurveda many krimighna drugs are mentioned. In this regard ‘Nimbapanchaka Churna’, having krimighna property mentioned in “Yogaratnakara†( shloka -04 in Krimirog chikitsa Adhyaya) is selected.
All that drugs possess properties mentioned for krimighna drugs.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Open Label
入排标准
- 年龄范围
- 3.00 Year(s) 至 12.00 Year(s)（—）
- 性别
- All
入选标准
- •Patientsirrespective of their gender, religion, & socioeconomic status 2)patients exhibiting symptoms of purishaja krimi mentioned in texts like udarshool, agnimandya, panduta, gudakandu.
排除标准
- •Patients below age 3 and above 12 year.
- •Patients presenting with complications occurred due to nematodes infestation 3)Any other systemic diseases which interfere with long term treatment.
- •Patient requiring surgical intervention.
- •Patient with symptoms like Abdominal pain affecting daily activities, Whitish pallor with skin pigmentation, Anal itching with disturbance of activity &sleep.
结局指标
主要结局
Udarshool (Abdominal pain)
时间窗: Baseline- 7th, 14th day
Panduta (Pallor)
时间窗: Baseline- 7th, 14th day
Agnimandya(Loss Of Apetite)
时间窗: Baseline- 7th, 14th day
Gudakandu (Anal Itching)
时间窗: Baseline- 7th, 14th day
次要结局
- Panduta (Pallor)(Agnimandya(Loss Of Apetite))