Improving Psychodynamic Psychotherapy in Primary Care: Randomised Evaluation of Dynamic Interpersonal Therapy (DIT)

Not Applicable

Completed

• Conditions: Topic: Mental Health Research Network; Subtopic: Depression; Mental and Behavioural Disorders; Disease: Depression; Depressive episode, unspecified

• Registration Number: ISRCTN38209986
• Lead Sponsor: Tavistock and Portman NHS Foundation Trust (UK)

Brief Summary

2019 results in: https://www.ncbi.nlm.nih.gov/pubmed/31084635 (added 21/06/2019)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-06-22
• Study Completion: 2016-12-31
• Last Update Posted: 15 July 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. Aged over 18 years, male or female
2. Current diagnosis of Major depressive disorder (MDD) with or without dysthymic disorder according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria
3. Hamilton Depression Rating Scale score above 14
4. Patient Health Questionnaire (PHQ) score above 10
5. Confirmed need for high-intensity treatment either at triage, following referral, or by low-intensity worker and supervisor

Exclusion Criteria

1. Current psychotic symptoms or bipolar disorder
2. Current use of antipsychotic medication
3. Complex Personality Disorder
4. Historic or current self-injury/parasuicide
5. Historic or current eating disorder
6. Current excessive use of drugs/alcohol
7. Non-English speaking
8. Participation in another depression clinical trial within the last year where subject has received CBT
9. Previous unsuccessful CBT treatment
10. Clinical contra-indication to short-term psychotherapy (e.g. attachment history - multiple separations, serious ongoing trauma in childhood, multiple care-givers - suggesting the need for longer term psychotherapy)
11. Evidence of pervasive use of help
12. Highly unstable or insecure life arrangements (e.g. domestic violence)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> Primary outcome as of 14/06/2016:<br> Depression severity is measured using a semi-structured interview, the Hamilton Depression Rating Scale (HDRS-17) at baseline, mid-treatment (8 weeks), end-of-treatment (approx. 16 weeks), and long-term follow-ups (52 and 86 weeks).<br><br> Original primary outcome:<br> Hamilton Depression Rating Scale (HDRS-17) at baseline, mid-treatment (8 weeks) end-of-treatment (approx. 16 weeks)<br>