临床试验/CTRI/2025/06/089333

CTRI/2025/06/089333尚未招募2 期

Comparative study between lignocaine nebulization with and without dexmedetomidine in patients undergoing awake fiberoptic intubation following airway block : a randomized controlled trial.

Department of Anaesthesiology1 个研究点分布在 1 个国家目标入组 90 人开始时间: 2025年7月10日最近更新: 2025年6月21日

试验速览

阶段: 2 期
状态: 尚未招募
发起方
入组人数: 90
试验地点: 1
主要终点: Intubation time after adding dexmedetomidine with lignocaine nebulization as additive to airway block during awake fiberoptic intubation

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

This study is a randomized , double-blinded trial comparing lignocaine nebulization with and without dexmedetomidine in patients undergoing awake fiberoptic intubation in IPGME&R ,Kolkata.The primary outcome measures intubation time .Secondary outcomes measures cough severity score, Intubating condition, Patient comfort score, Hemodynamic changes and complications if any.

研究设计

研究类型: Interventional
分配方式: Randomized
盲法: Participant and Outcome Assessor Blinded

入排标准

年龄范围: 18.00 Year(s) 至 65.00 Year(s)（—）
性别: All

入选标准

•Patients that have given written, informed consent to participate the study, American Society of Anaesthesiologist physical status 1 , patients undergoing surgery under general anaesthesia.

排除标准

•Refusal to participate study, Allergy to local anaesthetics or any of the study drugs, pregnant and lactation, contraindication to regional nerve block like bleeding disorder and infection at the site of block, emergency operation.

结局指标

主要结局

Intubation time after adding dexmedetomidine with lignocaine nebulization as additive to airway block during awake fiberoptic intubation

时间窗: At the time from passing the fiberoptic endoscope tip through the nostril to the first reading obtained by the capnograph after endotracheal intubation

次要结局

Cough severity score, Intubating condition, Patient comfort score, Hemodynamic changes and Complications if any(16 months)

研究者

发起方

Department of Anaesthesiology

申办方类型

Government medical college

责任方

Principal Investigator

主要研究者

Anwesha Mandal

IPGMER and SSKM Hospital

研究点 (1)

Loading locations...

相似试验

尚未招募

不适用

To know the efficacy of drug lignocaine given through venous route to reduce pain after surgery and improve the quality of recovery when compared with another drug fentanyl also given through venous route in patients undergoing robotic and laparoscopic cancer surgeries

CTRI/2025/11/096748Dr Rajasree O60

尚未招募

不适用

Comparison of inhaling lignocaine to IV administration of lignocaine to decrease blood pressure spikes during throat tube insertion, finding both effective with IV being slightly better.

CTRI/2025/04/085320Gandhi Medical College and Associated hospitals70

尚未招募

4 期

A study comparing the effects on heart rate and blood pressure when using two different medicines 4 percentage lignocaine and 1 microgram per kg dexmedetomidine given as a mist through a mask before inserting a breathing tube

CTRI/2025/08/092488Government Medical College and Hospital104

招募中

不适用

Comparison of Anesthetic Efficacy OF 2% Lidocaine Inferior Alveolar Nerve (IANB) Block Versus Primary Buccal Infilteration With 4% Articaine in Symptomatic Irreversible Pulpitis(SIP) IN Mandibular First Molars

NCT07409896Armed Forces Institute of Dentistry, Pakistan330

尚未招募

1 期

Comparison between lignociane pretreatment and lignociane mixed with propofol for propofol induced pain

CTRI/2025/02/080233Dr SUMANTH S140