NCT02883400已完成4 期
Spironolactone to Prevent or Delay Calcineurin Inhibitor (CNI) Toxicity in Liver Transplant Recipients
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Glomerular Filtration Rate (GFR)
研究概览
简要总结
To study spironolactone to prevent calcineurin inhibitor (CNI) kidney injury.
详细描述
The aim of this study is to determine if spironolactone decreases nephrotoxicity from calcineurin inhibitors in liver transplant recipients and to determine the best study of renal function in liver transplant recipients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •liver transplant
排除标准
- •dual organ transplant
研究组 & 干预措施
spironolactone
Experimental
spironolactone
干预措施: Spironolactone (Drug)
结局指标
主要结局
Glomerular Filtration Rate (GFR)
时间窗: 18 months
The primary analyses were based on the difference between each estimated GFR measure and iothalamate scan.
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
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