Application of Ultrasound Integrated Precision Diagnosis Technology in Prevention of Kidney Disease and Its Progress
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Diagnostic Imaging
- Sponsor
- RenJi Hospital
- Enrollment
- 208
- Locations
- 2
- Primary Endpoint
- Number of patients with creatinine increasing by more than 50%
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
In this study, a prospective, randomized and controlled clinical study would be carried out to establish Ultrasound Integrated Precision Diagnosis Technology with elastography as the core technology to evaluate renal injury and repair comprehensively and accurately, and to improve the clinical diagnosis chance of renal injury (or renal fibrosis).
Combined with the dynamic changes of biomarkers (inflammatory factors, cytokines secreted by immune cells, etc.) after kidney injury, the research on the prognosis of kidney disease with ultrasound elastography technology as the core would be explored, which aims to provide a scientific basis for the application of Ultrasound Integrated Precision Diagnosis Technology.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Number of patients with creatinine increasing by more than 50%
Time Frame: 1st month-12 month
Number of patients with creatinine increasing by more than 50% of baseline.
Rate of death
Time Frame: 1st month-12 month
for all patients
Number of patients with initiation of continuous renal replacement therapy
Time Frame: 1st month-12 month
for non-transplantation patient
Secondary Outcomes
- Number of patients with cardiovascular events(1st month-12 month)
- Number of patients with new serious infections requiring hospitalization(1st month-12 month)
- Number of patients with cerebrovascular events(1st month-12 month)