Breast Lesions Characterization on Contrast Enhanced Ultrasound With Histopathological Correlation
Overview
- Phase
- Not Applicable
- Intervention
- Sonovue, Bracco
- Conditions
- Malignant Neoplasm, Overlapping Lesion of Breast
- Sponsor
- Rambam Health Care Campus
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- Tumor vascularization
- Last Updated
- 11 years ago
Overview
Brief Summary
Breast lesions are a common condition, diagnosed by imaging and palpation. In order to reduce the number of biopsies performed to the definitive diagnosis of a breast lesion, an imaging method with a high degree of accuracy is needed. Ultrasound imaging with microbubbles contrast media allows the diagnosis of vascularization of the lesion, according to timing. Our hypothesis is that a highly vascularized lesion that enhances in an early timing is most likely to represent a malignant lesion and thus, deserves biopsy for a definitive diagnosis. Females over 18 years age, with a focal lesion in breast will be suitable to perform this examination.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Female with a diagnosed breast focal lesion
Exclusion Criteria
- •Allergic conditions to contrast media,
- •R-L shunt
Arms & Interventions
Microbubbles contrast media for US
Sonovue, Bracco, microbubbles contrast media
Intervention: Sonovue, Bracco
Outcomes
Primary Outcomes
Tumor vascularization
Time Frame: one year