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Comparison of 1 vs 3 Sets of Resistance Training on Muscular Hypertrophy

Not Applicable
Completed
Conditions
Obesity
Interventions
Other: Amount of resistance offered in training
Registration Number
NCT01107691
Lead Sponsor
University of Kansas
Brief Summary

This study is designed to investigate the effects of two levels of resistance weight training on body composition, energy expenditure, and energy intake in men and women. The weight training will take about one hour to complete. Participants will perform the training 3 days per week for 9 months in a private exercise room equipped with state of the art equipment and a personal trainer to help guide you through the exercises.

The project lasts 21 months total with one follow-up visit 1-year from your last training date. You will be required to stay in the Lawrence area and train 3 day/week over the summer \& holidays.

Detailed Description

We propose to conduct a randomized controlled efficacy trial (RT-1 set vs. RT-3 sets vs. non exercise control) to evaluate the potential for a longer intervention (9 months RT with body composition assessments 1 yr post RT completion) with a higher volume of RT (3 sets) to enhance the effects on body composition and energy expenditure observed in the pilot, and to determine the impact of the 2 levels of RT on free-living energy balance (expenditure by doubly labeled water and intake by digital photography and 24-hr recalls). This investigation will be conducted in a sample of healthy, normal and overweight, sedentary, young adult men and women; a group at high risk for development of overweight and obesity. The specific aims of this project are to determine the impact of the volume (1 vs. 3 sets) of a progressive RT protocol for inducing muscular hypertrophy, as recommended by the American College of Sports Medicine, on body weight and body composition (fat mass, fat-free mass (FFM), % body fat) and energy balance. Our results will provide information relative to the minimum volume of RT that may be associated with body weight/fat gain which may inform the development of guidelines for RT to prevent weight gain or to alter body composition. If RT has a favorable impact on energy balance and body composition, it may provide an attractive alternative to aerobic exercise for weight management for busy young adults, as RT requires minimal time, and no need to change clothes or shower (i.e. minimal or no sweating).

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
169
Inclusion Criteria
  • BMI 22-<30
  • 18- 30 years old
  • sedentary
  • no medications
  • weight stable for at least 3 months
Exclusion Criteria
  • Tobacco/Drug user
  • metabolism altering medication
  • gain/lost 10lbs in the last 3 months
  • current exerciser

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Resistance trainingAmount of resistance offered in training1 set of progressive resistance training per session
3 sets per sessionAmount of resistance offered in training3 sets of progressive resistance training per session
Primary Outcome Measures
NameTimeMethod
Body Composition21 Months

Changes in body composition will be evaluated by measuring the change in percent body fat, total fat mass, and total lean mass by dual energy x-ray absorptiometry (DEXA).

Secondary Outcome Measures
NameTimeMethod
Resting Metabolic Rate9 months

Resting metabolic rate as measured by indirect calorimetry as kcal/day will be evaluated. Also, substrate oxidation (fat and carbohydrate oxidation) will be evaluated at these time points.

Muscular Strength9 months

One rep max strength will be measured on the chest and leg press.

Daily Energy Expenditure9 months

Total daily energy expenditure over a 14 day period will be measured using doubly labeled water.

Trial Locations

Locations (1)

Energy Balance Lab, The University of Kansas

🇺🇸

Lawrence, Kansas, United States

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