Effects of Anti-stress Therapy on behavior and stress hormones in infertile women and also on weight loss after diet and exercise guidance in those overweight

Not Applicable

• Conditions: infertility , obesity; C12.294.365; C18.654.726.500

• Registration Number: RBR-7by76r
• Lead Sponsor: Hospital das Clínicas da Universidade Federal de Minas Gerais

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-04-25
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Data analysis completed
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Infertility; policystic ovarian syndrome; uterus, tube and/or ovarian disfuctions; overweight; obesity.

Exclusion Criteria

Refuse to sign the Informed Consent; give up the project.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Variation of stress in infertile patients assessed through the Stress Symptoms Inventory Lipp in Adults by detecting presence or absence of stress in pre and post intervention measurements.<br><br>Variation of body mass index in infertile patients assessed through body weight by detecting at least 10% variationin pre and post intervention measurements.

Secondary Outcome Measures

Name	Time	Method
Variation of capillary cortisol level in infertile patients assessed using ELISA assay by detecting at least 3 microg/dl in the pre and post intervention measurements.<br><br>Variation of plasma cortisol level in infertile patients assessed using ELISA assay by detecting at least 350 nMol/L in pre and post intervention measurements. <br><br>Variation of plasma NPY level in infertile patients assessed using ELISA assay by detecting at least 30 pMol/L in pre and post intervention measurements. <br><br>Variation of plasma level of the neurotrophic factors BDNF, NGF and BDNF in infertile patients assessed using ELISA assay by detecting at least 10% in pre and post intervention measurements.<br><br>Adherence to the prescribed diet in infertile patients verified by food diary by detecting at least 80% adherence.<br><br>Variation of quality of life in infertile patients assessed through the Psicological General Well Being Inventary by detecting at least 10 points in pre and post intervention measurements.