Combined Systemic Inflammatory Indices and Birth Weight

Completed

• Conditions: Systemic Inflammation Markers; Birth Weight; Combined Systemic Inflammatory Indices
• Interventions: Diagnostic Test: None intervention

• Registration Number: NCT06325735
• Lead Sponsor: University of Campania "Luigi Vanvitelli"

Brief Summary

The study aimed to explore the complex relationship between various systemic inflammatory indices and birth weight

Detailed Description

The research was structured as a prospective observational study. It was conducted at a second-level University Hospital over the period from December 2019 to February 2021.

Participants:

Blood samples were collected at hospital admission. These samples were used for a complete blood count, focusing specifically on deriving systemic inflammatory indices.

The primary inflammatory indices studied were Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR), and Monocyte-to-Lymphocyte Ratio (MLR).

The birth weight was registered.

Study Timeline

• Study Start: 2019-12-01
• Primary Completion: 2021-02-01
• Study First Submitted: 2024-03-10
• Study First Submitted QC: 2024-03-19
• Study First Posted: 2024-03-22
• Status Verified: 2024-04
• Study Completion: 2024-04-01
• Last Update Submitted: 2024-04-16
• Last Update Posted: 2024-04-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 199

Inclusion Criteria

• physiological Full-term pregnancies

Exclusion Criteria

• gestational diabetes
• pregestational diabetes
• Chronic Hypertension
• Gestational Hypertension
• Preeclampsia
• Eclampsia
• Intrauterine Fetal Growth Restriction
• Preterm Delivery
• Multiple Pregnancies
• Fetal malformations

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
full term pregnancy	None intervention	Total Participants: The study included full-term pregnant women. Exclusion Criteria: Participants were carefully selected, excluding those with specific conditions that could confound the study results. These conditions included gestational and pregestational diabetes, chronic hypertension, gestational hypertension, pre-eclampsia/eclampsia, intrauterine fetal growth restriction, preterm delivery, multiple pregnancies, and prenatally detected fetal abnormalities.

Primary Outcome Measures

Name	Time	Method
Systemic inflammatory indices and birth weight	3 months	investigate the correlation between systemic inflammatory indices and birth weight in full-term pregnancies

Trial Locations

Locations (1)

Università degli studi della Campania "Luigi Vanvitelli"- OB & Gyn -; 🇮🇹 Napoli, Italia, Italy