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Clinical Trials/NCT06270368
NCT06270368
Recruiting
N/A

Children Born Preterm: Sustainable Health Monitoring

Meyer Children's Hospital IRCCS4 sites in 1 country650 target enrollmentAugust 5, 2020
ConditionsPremature Birth

Overview

Phase
N/A
Intervention
Not specified
Conditions
Premature Birth
Sponsor
Meyer Children's Hospital IRCCS
Enrollment
650
Locations
4
Primary Endpoint
Childhood development
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

Children born preterm are recognized to be at higher risk of short and long term complications and a formal follow-up of infants and children born preterm is recommended by international and national scientific societies. However, in Italy as well as in Tuscany, such a follow up is not usually done, and data are not collected in a structured way. The goal of this observational study is to evaluate the association between a large number of early life exposures and health outcomes and access to care during childhood in infants born preterm. The main questions it aims to answer are: • what is the role of prenatal and perinatal factors in influencing health outcomes during childhood in preterm infants? • What is the role of prenatal and perinatal factors in influencing access to care during childhood? Participants will be asked to attend a follow-up visit for the purpose of collecting health data.

Registry
clinicaltrials.gov
Start Date
August 5, 2020
End Date
December 31, 2025
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Meyer Children's Hospital IRCCS
Responsible Party
Principal Investigator
Principal Investigator

Vieri Lastrucci

MD

Meyer Children's Hospital IRCCS

Eligibility Criteria

Inclusion Criteria

  • Children born preterm (gestational age below 37 weeks at birth) in Tuscany Region
  • Acquisition of the informed consent

Exclusion Criteria

  • Residing outside Tuscany region

Outcomes

Primary Outcomes

Childhood development

Time Frame: The measurements will be assessed at 56-66 months of age

Childhood development comprises physical, cognitive, social-emotional, linguistic, and behavioral milestones. Childhood development is assessed with the Ages and Stages Questionnaires (ASQ-3).

Infant development

Time Frame: The measurements will be assessed at 20-28 months of age

Infant development comprises physical, cognitive, social-emotional, linguistic, and behavioral milestones. Infant development is assessed with the Bayley Scales Of Infant and Toddler Development third edition (Bayley - III).

Secondary Outcomes

  • Presence of asthma(The measurements will be assessed at 56-66 months of age)
  • Presence of visual or hearing impairement(The measurements will be assessed at 20-28 months of age and at 56-66 months of age)
  • Access to care(The measurements will be assessed at 20-28 months of age and at 56-66 months of age)

Study Sites (4)

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