NCT05524207招募中不适用
A Controlled Clinical Study of Carotid Artery Stent Implantation in the Treatment of Vulnerable Plaque
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Perioperative 30-day stroke rate
研究概览
简要总结
To investigate the efficacy and safety of carotid stenting for vulnerable carotid plaques. All patients with carotid artery stenosis underwent carotid arterial contrast-enhanced ultrasonography before operation. According to the examination results, they were divided into two groups: vulnerable plaque group and stable plaque group. The incidence of perioperative stroke events in the two groups was compared. The incidence of stroke events in the two groups within 1 year was compared.
详细描述
- To enroll 100 cases of patients suffering from carotid artery stenosis。the investigators perform contrast enhanced ultrasound on patients for identifying the vulnerable plagues
- The investigators divide patients into the stable group and the vulnerable group based on the results of CEUS inspection.
- All patients undergo carotid stent. To analysis the incidence of postoperative complications such as stroke and mortality within 30 days and to compare the differences between the two groups.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The patients with ischemic symptom whose carotid stenosis were more than 50%
- •The patients without ischemic symptom whose carotid stenosis were more than 70%
排除标准
- •• Confirmed with severe intracranial vascular lesions
- •Suffering from the large area cerebral infarction or critical stroke sequela
- •Restenosis after CEA or CAS
- •Suffering from severe coronary heart disease, respiratory failure,the hypertension difficult to controled
- •Patients with malignant tumor or expected life < 2 years
结局指标
主要结局
Perioperative 30-day stroke rate
时间窗: 30 days
To determine whether there is a new cerebral infarction by postoperative re-examination of brain MRI and preoperative brain MRI
次要结局
- 1-year stroke rate after surgery(1 year)
研究者
Keqiang Zhao
Attending Doctor
Beijing Tsinghua Chang Gung Hospital
研究点 (1)
Loading locations...
相似试验
已完成
不适用
A Randomized Trial of Carotid Artery Stenting With and Without Cerebral ProtectionCarotid Artery StenosisNCT00177346University of Pittsburgh52
已完成
4 期
A Single Center of Carotid Stenting With Distal Protection for the Treatment of Obstructive Carotid Artery DiseaseHeart DiseaseBrain Vascular AccidentCarotid Artery DiseaseCarotid StenosisNCT00178672The University of Texas Health Science Center, Houston69
招募中
不适用
Timing Carotid Stent Clinical Study for the Treatment of Carotid Artery Stenosis（Timing Trial）Carotid Artery DiseasesIschemic StrokeStrokeCarotid Artery StenosisNCT05574972Suzhou Zenith Vascular Scitech Co., Ltd.178
已完成
不适用
Carotid Artery Stenting Without ProtectionCarotid ArteriesNCT02781181Acibadem University279
已完成
2 期
Carotid With Bivalirudin AngioplastyCarotid Artery DiseaseNCT00812383Medstar Health Research Institute299