Myeloid-derived Suppressor Cells in Sepsis

• Conditions: Sepsis

• Registration Number: NCT03540797
• Lead Sponsor: Chung Fu-Tsai

Brief Summary

This study is designed for septic patients, to isolate MDSCs and the correlation of prognosis of sepsis. The purpose of this study hopes to explore the phenomenon and possible mechanisms of MDSCs in patients with severe sepsis.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-07-01
• Status Verified: 2018-05
• Study First Submitted: 2018-05-17
• Study First Submitted QC: 2018-05-17
• Study First Posted: 2018-05-30
• Last Update Submitted: 2018-05-30
• Last Update Posted: 2018-05-31
• Primary Completion: 2023-12-31
• Study Completion: 2023-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 125

Inclusion Criteria

• Patients must have known origin of infection .
• Systemic inflammatory response syndrome.

Exclusion Criteria

• age less than 18 years
• pregnancy
• known anaphylactoid reaction to colloid fluids
• a life expectancy less than 24 hours,
• inability to provide informed, written consent
• Patients receiving nephrotoxic drugs,
• admitted to the hospital following a surgical procedure,
• sepsis more than 72 hours when screening .

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Survival of Intensive care unit (ICU) stay	28 days

Secondary Outcome Measures

Name	Time	Method
In hospital survival	90 days

Trial Locations

Locations (1)

Chung Gung Memorial Hospital; 🇨🇳 Linkou, Taiwan