Risk Factors for Predictors of Major Adverse Cardiovascular Events After Coronary Artery Bypass Using Radial Artery Grafts
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Coronary Artery Disease
- Sponsor
- Ruijin Hospital
- Enrollment
- 370
- Locations
- 1
- Primary Endpoint
- 7-day MACE-4
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
As the secondary choice of artery grafts, radial artery is more and more used to achieve multiple arterial revascularization in CABG. Risk factors for predictors of major cardiovascular adverse events (MACE) after CABG using radial-artery grafts (RA-CABG), however, remain uncertain. This case-control study aims to identify the baseline predictors of MACE after RA-CABG.
We will collect the baseline characteristics and perioperative data of patients underwent RA-CABG from Jan. 2009 to Dec. 2019 in our single center. By reviewing the latest follow-up records, we will examine the correlation between the baseline characteristics and clinical outcomes (MACEs), then identify the independent risk factors for predictors of MACEs after RA-CABG.
Investigators
Qiang Zhao,MD
Professor and Director, Department of Cardiovascular Surgery, Vice President, Ruijin Hospital
Ruijin Hospital
Eligibility Criteria
Inclusion Criteria
- •Underwent CABG using at least a radial artery grafts from Jan.2009 to Dec.
- •with or without cardiopulmonary bypass , with or without concomitant procedure
- •Aged 18 and above at procedure
- •With any gender
Exclusion Criteria
- •With unavailable medical records
Outcomes
Primary Outcomes
7-day MACE-4
Time Frame: 7 days post-CABG
a composite of all-cause death, myocardial infraction, stroke and repeat revascularization
30-day MACE-4
Time Frame: 30 days post-CABG
a composite of all-cause death, myocardial infraction, stroke and repeat revascularization
1-year MACE-4
Time Frame: 1 year post-CABG
a composite of all-cause death, myocardial infraction, stroke and repeat revascularization
3-year MACE-4
Time Frame: 3 years post-CABG
a composite of all-cause death, myocardial infraction, stroke and repeat revascularization
Secondary Outcomes
- MACE-3(7 days, 30 days, 1 year, and 3 years post-CABG)
- All-cause death(7 days, 30 days, 1 year, and 3 years post-CABG)
- CV-death(7 days, 30 days, 1 year, and 3 years post-CABG)
- Myocardial infraction(7 days, 30 days, 1 year, and 3 years post-CABG)
- Stroke(7 days, 30 days, 1 year, and 3 years post-CABG)
- Repeat revascularization(7 days, 30 days, 1 year, and 3 years post-CABG)