Perioperative Transfusion Related Outcome

Completed

• Conditions: Blood Transfusion
• Interventions: Other: Control; Other: Blood transfusion

• Registration Number: NCT03930355
• Lead Sponsor: Diskapi Teaching and Research Hospital

Brief Summary

A secondary analysis of the Turkish National Perioperative Transfusion Study (TULIP TS) database will be performed.

Detailed Description

The Turkish National Perioperative Transfusion Study (TULIP TS) was conducted by The Turkish Society of Anesthesiologists' Multicentre Clinical Trials Network.

TULIP TS included 6481 patients undergoing major elective surgery, from 61 study sites across the country.

Transfusion practices of clinicians working at diverse surgical fields; differences between current transfusion practices and patient blood management strategies; the areas for improvement and the obstacles that could prevent change were evaluated and identified.

Data relevant to perioperative transfusion rates of red blood cells, fresh frozen plasma and platelets, the indications for transfusion and postoperative adverse outcomes including 1 month all cause mortality was obtained.

The TULIP TS group aims to collect further data concerning 1 year all cause mortality of the same patient population and to evaluate adverse outcomes in transfused and non transfused patients.

Study Timeline

• Study First Submitted: 2019-04-24
• Study First Submitted QC: 2019-04-25
• Study First Posted: 2019-04-29
• Study Start: 2019-05-01
• Status Verified: 2020-06
• Primary Completion: 2020-12-30
• Study Completion: 2020-12-30
• Last Update Submitted: 2021-09-23
• Last Update Posted: 2021-09-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 6121

Inclusion Criteria

• Patients undergoing major elective surgery

Exclusion Criteria

• Trauma patients, emergency surgery

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Non transfused	Control	Patients who did not receive blood transfusion in the perioperative period
Transfused	Blood transfusion	Patients who received blood transfusion in the perioperative period

Primary Outcome Measures

Name	Time	Method
Infection	postoperative 30th day	Number of participants with infection
Acute kidney injury	postoperative 30th day	Number of participants with acute kidney injury
Thromboembolic event	postoperative 30th day	Number of participants with a thromboembolic event
1 year all cause mortality	postoperative 366th day	Number of participants died: all cause mortality
Acute respiratory failure	postoperative 30th day	Number of participants with acute respiratory failure
Ischemic event	postoperative 30th day	Number of participants with an ischemic event
Myocardial infarction	postoperative 30th day	Number of participants with myocardial infarction
Adverse cardiac event	postoperative 30th day	Number of participants with an adverse cardiac event

Trial Locations

Locations (60)

University of Health Sciences Ankara Training and Research Hospital; 🇹🇷 Ankara, Turkey

Diskapi Yildirim Beyazit Teaching and Research Hospital; 🇹🇷 Ankara, Turkey

Private Cankaya Hospital; 🇹🇷 Ankara, Turkey

Acibadem University Mehmet Ali Aydinlar Atakent Hospital; 🇹🇷 Ankara, Turkey

Ufuk University Medical Faculty Dr. Ridvan Ege Training and Research Hospital; 🇹🇷 Ankara, Turkey

Ankara University Ibni Sina Hospital; 🇹🇷 Ankara, Turkey

Ankara University Cebeci Medical Center; 🇹🇷 Ankara, Turkey

Gazi University Medical Faculty; 🇹🇷 Ankara, Turkey

Hacettepe University Medical Faculty; 🇹🇷 Ankara, Turkey

University of Health Sciences Ankara Numune Training and Research Hospital; 🇹🇷 Ankara, Turkey

University of Health Sciences Diskapi Yildirim Beyazit Trainig Research Hospital; 🇹🇷 Ankara, Turkey

University of Health sciences Ankara Child Health and Diseases Hematology Oncology Training and research Hospital; 🇹🇷 Ankara, Turkey

University of Health Sciences Kecioren Training and Research Hospital; 🇹🇷 Ankara, Turkey

University of Health Sciences Dr Abdurrahman Yurtaslanı Ankara Oncology Training and Research Hospital; 🇹🇷 Ankara, Turkey

University of Health Sciences Turkiye Yuksek Ihtisas Training and Research Hospital; 🇹🇷 Ankara, Turkey

University of Health Sciences Zubeyde Hanim Gynecology and Maternity Training and Research Hospital; 🇹🇷 Ankara, Turkey

University of Health Sciences Yenimahalle Training and Research Hospital; 🇹🇷 Ankara, Turkey

Akdeniz University Medical Faculty; 🇹🇷 Antalya, Turkey

University of Technology and Economics Medical Faculty; 🇹🇷 Ankara, Turkey

University of Health Sciences Antalya Training and Research Hospital; 🇹🇷 Antalya, Turkey

Balikesir University Training and Research Hospital; 🇹🇷 Balıkesir, Turkey

Uludağ University Medical Faculty; 🇹🇷 Bursa, Turkey

Trakya University Medical Faculty; 🇹🇷 Edirne, Turkey

Fırat University Medical Faculty; 🇹🇷 Elazığ, Turkey

University of Health Sciences Bursa Yuksek Ihtisas Training and Research Hospital; 🇹🇷 Bursa, Turkey

Erzincan University Mengucek Gazi Training and Research Hospital; 🇹🇷 Erzincan, Turkey

Başkent University Ankara Hospital; 🇹🇷 Ankara, Turkey

Eskisehir Osmangazi University Medical Faculty; 🇹🇷 Eskişehir, Turkey

Acibadem University Altunizade Hospital; 🇹🇷 Istanbul, Turkey

Istanbul University Medical Faculty; 🇹🇷 Istanbul, Turkey

Suleyman Demirel University Medical Faculty; 🇹🇷 Isparta, Turkey

Marmara University Pendik Training and Research Hospital; 🇹🇷 Istanbul, Turkey

University of Health Sciences Istanbul Training and Research Hospital; 🇹🇷 Istanbul, Turkey

University of Health Sciences Fatih Sultan Mehmet Training and Research Hospital; 🇹🇷 Istanbul, Turkey

Inonu University Liver Transplantation Institute; 🇹🇷 Malatya, Turkey

University of Health Sciences Haydarpasa Numne Training and Research Hospital; 🇹🇷 Istanbul, Turkey

University of Health Sciences Okmeydanı Training and Research Hospital; 🇹🇷 Istanbul, Turkey

University of Health Sciences Bozyaka Training Research Hospital; 🇹🇷 İzmir, Turkey

Erciyes University Medical Faculty; 🇹🇷 Kayseri, Turkey

University of Health Sciences Kanuni Sultan Suleyman Training and Research Hospital; 🇹🇷 Istanbul, Turkey

University of Health Sciences Umraniye Training and Research Hospital; 🇹🇷 Istanbul, Turkey

Dokuz Eylul University Medical Faculty; 🇹🇷 İzmir, Turkey

Sutcu Imam University Medical Faculty; 🇹🇷 Kahramanmaraş, Turkey

Selcuk University Medical Faculty; 🇹🇷 Konya, Turkey

Mersin University Medical Faculty; 🇹🇷 Mersin, Turkey

University of Health Sciences İzmir Tepecik Training and Research Hospital; 🇹🇷 İzmir, Turkey

Anadolu Health Center Hospital; 🇹🇷 Kocaeli, Turkey

University of Health Sciences Konya Training and Research Hospital; 🇹🇷 Konya, Turkey

Necmettin Erbakan University Meram Medical Faculty Center for Health and Research; 🇹🇷 Konya, Turkey

University of Health Sciences Derince Training and Research Hospital; 🇹🇷 Kocaeli, Turkey

Manisa Celal Bayar University Medical Faculty Hafsa Sultan Hospital; 🇹🇷 Manisa, Turkey

Ordu University Medical Faculty; 🇹🇷 Ordu, Turkey

Osmaniye State Hospital; 🇹🇷 Osmaniye, Turkey

Namık Kemal University Medical Faculty; 🇹🇷 Tekirdağ, Turkey

Ondokuz Mayıs University Medical Faculty; 🇹🇷 Samsun, Turkey

Karadeniz Technical University Medical Faculty Farabi Hospital; 🇹🇷 Trabzon, Turkey

Tunceli State Hospital; 🇹🇷 Tunceli, Turkey

Van Yuzuncuyıl University Medical Faculty Dursun Odabası Center; 🇹🇷 Van, Turkey

Bulent Ecevit University Medical Faculty Center for Health and Research; 🇹🇷 Zonguldak, Turkey

Hitit University Corum Erol Olcok Training and Research Hospital; 🇹🇷 Çorum, Turkey