Effect of Perioperative Transfusion on Early and Late Outcome After Major Elective Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Blood Transfusion
- Sponsor
- Diskapi Teaching and Research Hospital
- Enrollment
- 6121
- Locations
- 60
- Primary Endpoint
- Acute kidney injury
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
A secondary analysis of the Turkish National Perioperative Transfusion Study (TULIP TS) database will be performed.
Detailed Description
The Turkish National Perioperative Transfusion Study (TULIP TS) was conducted by The Turkish Society of Anesthesiologists' Multicentre Clinical Trials Network. TULIP TS included 6481 patients undergoing major elective surgery, from 61 study sites across the country. Transfusion practices of clinicians working at diverse surgical fields; differences between current transfusion practices and patient blood management strategies; the areas for improvement and the obstacles that could prevent change were evaluated and identified. Data relevant to perioperative transfusion rates of red blood cells, fresh frozen plasma and platelets, the indications for transfusion and postoperative adverse outcomes including 1 month all cause mortality was obtained. The TULIP TS group aims to collect further data concerning 1 year all cause mortality of the same patient population and to evaluate adverse outcomes in transfused and non transfused patients.
Investigators
DILEK YAZICIOGLU
Assoc Prof
Diskapi Teaching and Research Hospital
Eligibility Criteria
Inclusion Criteria
- •Patients undergoing major elective surgery
Exclusion Criteria
- •Trauma patients, emergency surgery
Outcomes
Primary Outcomes
Acute kidney injury
Time Frame: postoperative 30th day
Number of participants with acute kidney injury
Thromboembolic event
Time Frame: postoperative 30th day
Number of participants with a thromboembolic event
Infection
Time Frame: postoperative 30th day
Number of participants with infection
1 year all cause mortality
Time Frame: postoperative 366th day
Number of participants died: all cause mortality
Acute respiratory failure
Time Frame: postoperative 30th day
Number of participants with acute respiratory failure
Ischemic event
Time Frame: postoperative 30th day
Number of participants with an ischemic event
Myocardial infarction
Time Frame: postoperative 30th day
Number of participants with myocardial infarction
Adverse cardiac event
Time Frame: postoperative 30th day
Number of participants with an adverse cardiac event