A comparative study comparing anxiety reducing effect of tablet Lorazepam and tablet Alprazolam.
Phase 3
- Conditions
- Health Condition 1: K829- Disease of gallbladder, unspecified
- Registration Number
- CTRI/2024/05/066874
- Lead Sponsor
- Sanjay Gandhi Post Graduate Institute of Medical sciences Lucknow Uttar pradesh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patient giving written consent.
2.Patients belonging to ASA grade I and II.
3.All genders
4.Normal BMI(18.5-25) subjects.
5.Patients in the age group (18-60years) undergoing elective laparoscopic cholecystectomy.
Exclusion Criteria
1. Patients not giving consent.
2. ASA grade III and IV.
3. Emergency surgeries.
4. Patient who had taken analgesic, sedative, antidepressant, and on antiepileptic drugs were excluded.
6. Patients with psychiatry illness will be excluded.
5. Patients with anticipated difficult airway.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary Objective – <br/ ><br>1.Comparison of Alprazolam and Lorazepam in terms of anxiolysis by Hamilton anxiety rating scale (HAM-A). <br/ ><br>2. Comparison of level of amnesia by MMSE score at time T1 and T2. <br/ ><br>Timepoint: At the time of giving premedication in the ward 3 hours prior to GA (T1), in the preoperative ward before shifting the patient to the operation theatre (T2)
- Secondary Outcome Measures
Name Time Method Secondary objectives – (i)Comparison of level of sedation by using Ramsey sedation score at time T1 & T2Timepoint: At the time of giving premedication in the ward 3 hours prior to GA (T1), in the preoperative ward before shifting the patient to the operation theatre (T2) <br/ ><br>