NCT02160613已完成不适用
Effect of Periodontal Surgery on Osteoprotegerin Levels in Gingival Crevicular Fluid, Saliva and Gingival Tissues.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Change from baseline in Osteoprotegerin levels at 3 and 6 months
研究概览
简要总结
The study hypothesis:
Is Osteoprotegerin a diagnostic and/or prognostic marker of periodontal disease?
详细描述
assessment of osteoprotegerin in patients with chronic periodontitis before and after periodontal surgery in gingival crevicular fluid, saliva and gingival tissues.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 32 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •severe chronic periodontitis, having pocket depth of ≥ 5 mm and clinical attachment level ≥ 5 mm
排除标准
- •pregnant women
- •subjects had <22 permanent teeth
- •having any given systemic disease
- •taking any type of medication and/or antibiotic therapy during the 3 months before the study
- •received periodontal treatment within the past 12 months
- •current or former smokers.
结局指标
主要结局
Change from baseline in Osteoprotegerin levels at 3 and 6 months
时间窗: Baseline, 3 months and 6 months
次要结局
- Changes from baseline in probing pocket depth at 3 and 6 months(baseline, 3 months and 6 months)
- changes from baseline in Clinical attachment level at 3 and 6 months.(Baseline, 3 months and 6 months)
- Changes from baseline in gingival index at 3 and 6 months(baseline, 3 months and 6 months)
- Changes from baseline in plaque index at 3 and 6 months(baseline, 3 months and 6 months)
研究者
Noha Ayman Ghallab
Associate Professor of periodontology, faculty of oral and dental medicine
Cairo University
研究点 (1)
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