Diet and Muscle Function In Older Adults

Not Applicable

Completed

• Conditions: Sarcopenia
• Interventions: Dietary Supplement: Whey protein supplementation; Dietary Supplement: Carbohydrate (polycose) supplementation

• Registration Number: NCT02069314
• Lead Sponsor: Purdue University

Brief Summary

This research study was conducted to investigate the effects of a high protein diet on the efficiency of energy use at rest and at low-levels of physical activity. The hypothesis was that a high intake of dietary protein would result in a less efficient use of energy in skeletal muscle in older adults.

Detailed Description

This research study was conducted to investigate the effects of a high protein diet on the efficiency of energy use at rest and at low-levels of physical activity. The hypothesis was that a high intake of dietary protein would result in a less efficient use of energy in skeletal muscle in older adult

Study Timeline

• Study Start: 2012-05
• Status Verified: 2013-05
• Primary Completion: 2013-05
• Study Completion: 2013-05
• Study First Submitted: 2014-02-12
• Study First Submitted QC: 2014-02-19
• Last Update Submitted: 2014-02-19
• Study First Posted: 2014-02-24
• Last Update Posted: 2014-02-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

• 65 years and older

Exclusion Criteria

• Diabetic
• Acute symptoms of cardiovascular disease or congestive heart failure
• uncontrolled hypertension
• supplemental oxygen consumption at rest or during exercise
• lactose intolerance
• inability to ride a stationary cycle

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Whey protein supplementation	Whey protein supplementation	50 grams of whey blended into frozen drink
Carbohydrate supplementation	Carbohydrate (polycose) supplementation	50 grams of polycose blended into frozen drink

Primary Outcome Measures

Name	Time	Method
Dietary protein effects on muscle energy use	participants will be measured over an average of 26 days	gross mechanical efficiency of muscle, consuming high and low protein supplements

Secondary Outcome Measures

Name	Time	Method
Effect of protein supplements on food intake	participants will be measured over an average of 26 days	effects of high protein or high carbohydrate supplements on overall energy consumption in older adults.

Trial Locations

Locations (1)

Purdue University; 🇺🇸 West Lafayette, Indiana, United States