跳至主要内容
临床试验/DRKS00011612
DRKS00011612进行中(未招募)未知

Dopamine’s role in premature decision-making in healthy humans - DRIPD

Psychiatrische Universitätsklinik ZürichKlinik für Psychiatrie, Psychotherapie und Psychosomatik0 个研究点目标入组 50 人开始时间: 2017年1月25日最近更新:
适应症

试验速览

阶段
未知
状态
进行中(未招募)
发起方
入组人数
50

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional
分配方式
Randomized controlled study
盲法
Blinded (masking used)

入排标准

年龄范围
18 Years 至 40 Years(—)
性别
Male

入选标准

  • Age from 18 to 40 years
  • European ancestry
  • Right-handedness
  • Written informed consent
  • Consent to adhere to the study protocol
  • Ability to adhere to the study protocol

排除标准

  • Serious past or present brain disease, brain injury or brain surgery
  • Any neurological or psychiatric disorders (past or present)
  • Nicotine/tobacco use of more than 10 cigarettes per week, or equivalent
  • Current use of recreational drugs
  • History of alcohol and/or drug abuse
  • Any current severe medical condition
  • Currently taking medication of any kind, in particular any known to interact with methylphenidate
  • Allergy to lactose (placebo) or to methylphenidate
  • Tachycardia >100 bpm, cardiac arrhythmia and/or QTc time >430 ms
  • Blood pressure outside of healthy range
  • History of severe kidney or liver disorder
  • Pacemaker, neurostimulator or any other head or heart implants
  • Any breathing difficulties
  • Claustrophobia
  • Dependence on a hearing aid
  • Bald head or dreadlocks (EEG only)
  • Inability to sit still (EEG) or lie still (MRI) for the duration of the experiment (sneezing, coughing,
  • itching, trembling, twitching, pain, etc.)
  • Subjects with MRI-incompatible metal parts in the body
  • Possibility of the presence of any metal fragments in the body (e.g., metal splinters, ballistic
  • wounds, shrapnel or surgical clips)

研究者

发起方
Psychiatrische Universitätsklinik ZürichKlinik für Psychiatrie, Psychotherapie und Psychosomatik

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