DRKS00011612进行中(未招募)未知
Dopamine’s role in premature decision-making in healthy humans - DRIPD
Psychiatrische Universitätsklinik ZürichKlinik für Psychiatrie, Psychotherapie und Psychosomatik0 个研究点目标入组 50 人开始时间: 2017年1月25日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 进行中(未招募)
- 发起方
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized controlled study
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 40 Years(—)
- 性别
- Male
入选标准
- •Age from 18 to 40 years
- •European ancestry
- •Right-handedness
- •Written informed consent
- •Consent to adhere to the study protocol
- •Ability to adhere to the study protocol
排除标准
- •Serious past or present brain disease, brain injury or brain surgery
- •Any neurological or psychiatric disorders (past or present)
- •Nicotine/tobacco use of more than 10 cigarettes per week, or equivalent
- •Current use of recreational drugs
- •History of alcohol and/or drug abuse
- •Any current severe medical condition
- •Currently taking medication of any kind, in particular any known to interact with methylphenidate
- •Allergy to lactose (placebo) or to methylphenidate
- •Tachycardia >100 bpm, cardiac arrhythmia and/or QTc time >430 ms
- •Blood pressure outside of healthy range
- •History of severe kidney or liver disorder
- •Pacemaker, neurostimulator or any other head or heart implants
- •Any breathing difficulties
- •Claustrophobia
- •Dependence on a hearing aid
- •Bald head or dreadlocks (EEG only)
- •Inability to sit still (EEG) or lie still (MRI) for the duration of the experiment (sneezing, coughing,
- •itching, trembling, twitching, pain, etc.)
- •Subjects with MRI-incompatible metal parts in the body
- •Possibility of the presence of any metal fragments in the body (e.g., metal splinters, ballistic
- •wounds, shrapnel or surgical clips)
研究者
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