Rotational thrombelastometry in oral anticoagulants

• Conditions: D68; Other coagulation defects

• Registration Number: DRKS00012821
• Lead Sponsor: Klinik für AnästhesiologieKlinikum der Universität MünchenLudwig-Maximilians-Universität

Brief Summary

Our study presents modified thromboelastometric tests with improved detection of even low DOAC concentrations in-vitro. The study thus complements the previously published data on dabigatran and rivaroxaban.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-01-11
• Study Completion: 2022-07-05
• Results First Posted: 2022-07-05
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. Written consent
2. Age >18 years

Exclusion Criteria

1. Myelodysplastic syndrome
2. Thrombopenia
3. Hereditary coagulation diseases

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in ROTEM-variables in EXTEM, NATEM, ECATEM und FIBTEM in comparison to blood samples without Rivaroxaban/Dabigatran

Secondary Outcome Measures

Name	Time	Method
Changes in ROTEM-variables ECATEM and diluted tissue factor test with and without substance specific catcher.