Lasers in Onychomycosis
- Conditions
- Onychomycosis
- Interventions
- Device: Laser
- Registration Number
- NCT05415852
- Lead Sponsor
- Cairo University
- Brief Summary
Onychomycosis is the most common nail disease, representing more than 50% of all onychopathies. Future studies on the absorption spectra of dermatophyte fungi will be needed to develop lasers that effectively exploit absorption differences in fungi and dermal tissue.
- Detailed Description
Treatments with antifungals may not be successful due to several factors, including the long time required to apply topical medications, the side effects of systemic drugs, and the application of insufficient medication to the target area. Even with adequate systemic or topical therapy, the persistence of fungal infections is not uncommon. In light of these limitations, laser therapy has been proposed as an alternative option for onychomycosis therapy.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 40
- Patients with onychomycosis.
- Patients with excessive manual work
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description fractional CO2 laser Laser Laser Nd Yag Laser Laser Pulsed dye laser Laser Laser Q switched Nd Yag Laser Laser
- Primary Outcome Measures
Name Time Method Onychomycosis severity index change from baseline at 3 months clinical assessment
- Secondary Outcome Measures
Name Time Method