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Lasers in Onychomycosis

Not Applicable
Conditions
Onychomycosis
Interventions
Device: Laser
Registration Number
NCT05415852
Lead Sponsor
Cairo University
Brief Summary

Onychomycosis is the most common nail disease, representing more than 50% of all onychopathies. Future studies on the absorption spectra of dermatophyte fungi will be needed to develop lasers that effectively exploit absorption differences in fungi and dermal tissue.

Detailed Description

Treatments with antifungals may not be successful due to several factors, including the long time required to apply topical medications, the side effects of systemic drugs, and the application of insufficient medication to the target area. Even with adequate systemic or topical therapy, the persistence of fungal infections is not uncommon. In light of these limitations, laser therapy has been proposed as an alternative option for onychomycosis therapy.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
40
Inclusion Criteria
  • Patients with onychomycosis.
Exclusion Criteria
  • Patients with excessive manual work

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
fractional CO2 laserLaserLaser
Nd YagLaserLaser
Pulsed dye laserLaserLaser
Q switched Nd YagLaserLaser
Primary Outcome Measures
NameTimeMethod
Onychomycosis severity indexchange from baseline at 3 months

clinical assessment

Secondary Outcome Measures
NameTimeMethod
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