Seroprevalence of SARS-CoV-2 antibodies in a quarantined community after a COVID-19 outbreak-the CoNAN study
- Conditions
- 07.1 COVID-19
- Registration Number
- DRKS00022416
- Lead Sponsor
- niversitätsklinikum Jena
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 626
Inclusion Criteria
inhabitants of Neustadt am Rennsteig
Exclusion Criteria
no inhabitants of Neustadt am Rennsteig
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The study objective is the longitudinal recording of the Covid-19 antibody status (seroconversion rate) of the population of Neustadt am Rennsteig at a defined distance from the end of quarantine in order to determine the asymptomatic infestation rate.
- Secondary Outcome Measures
Name Time Method The secondary objectives of the study are: i) Seroconversion rate in children (if necessary: via lateral flow assay); ii) determination of T-cell immunity; iii) characterization of transmission rates among household members as well as with other persons depending on the families adhered to preventive measures, age and symptomatology; iv) determination of<br>Risk factors for symptomatic vs. asymptomatic Covid19 courses v) Examination 18_05_04_Protocol_human_material studies 5/10 the rate of persistent virus excretion; (vi) modelling of possible infection chains; (vii) determination of incubation and generation times and reporting delays; viii) Assessment of the effectiveness of the quarantine measures.